Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. The
primary prevention of CVD is dependent upon the ability to identify high-risk individuals long …

Abstract Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial
and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra-and …

In addition to routine clinical laboratory tests (including natriuretic peptides and cardiac
troponins), other biomarkers are gaining attention for their utility in heart failure (HF) …

Abstract Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that play a central
role in the regulation of immune responses. Its release from epithelial and endothelial cells …

Acute myocardial infarction (AMI) is one of the major causes of morbidity and mortality
worldwide. The inflammation response during and after AMI is common and seems to play a …

Background: Misdiagnosis of acute aortic dissection (AAD) can lead to significant morbidity
and death. Soluble ST2 (sST2) is a cardiovascular injury–related biomarker. The extent to …

Suppression of tumorigenicity 2 (ST2, also known as interleukin [IL]-1 receptor–like-1) is an
IL-1 receptor family member with transmembrane (ST2L) and soluble isoforms (sST2). ST2L …

Interleukin (IL)-33 and its unique receptor, ST2, play a pivotal role in the immune response
to infection and stress. However, there have been conflicting reports of the role of IL-33 in …

Coronavirus SARS-CoV-2 has represented, and still represents, a real challenge from a
clinical, diagnostic and therapeutic point of view. During acute infection, the increased levels …

The IL-33/ST2 L signaling pathway is involved in the pathophysiological processes of
several diseases and mainly exerts anti-inflammatory and antifibrotic effects. Soluble …