British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Vedolizumab in IBD–lessons from real-world experience; a systematic review and pooled analysis

T Engel, B Ungar, DE Yung, S Ben-Horin… - Journal of Crohn's …, 2018 - academic.oup.com
Background Vedolizumab [VDZ] is an anti-integrin monoclonal antibody effective in
ulcerative colitis [UC] and Crohn's disease [CD]. Several real-world experience [RWE] …

Pregnancy outcomes in inflammatory bowel disease patients treated with vedolizumab, anti‐TNF or conventional therapy: results of the European CONCEIVE study

A Moens, CJ van der Woude… - Alimentary …, 2020 - Wiley Online Library
Background Women with inflammatory bowel diseases (IBD) often receive biologicals
during pregnancy to maintain disease remission. Data on outcome of vedolizumab‐exposed …

Safety of new biologics (vedolizumab and ustekinumab) and small molecules (tofacitinib) during pregnancy: a review

JP Gisbert, M Chaparro - Drugs, 2020 - Springer
Two new biological drugs (vedolizumab and ustekinumab) and one small molecule
(tofacitinib) have been recently approved for the treatment of inflammatory bowel disease …

Immunosuppressives and biologics during pregnancy and lactation: A consensus report issued by the Austrian Societies of Gastroenterology and Hepatology and …

A Puchner, HP Gröchenig, J Sautner… - Wiener klinische …, 2019 - Springer
An increasing and early-onset use of immunosuppressives and biologics has become more
frequently seen among patients with inflammatory bowel diseases (IBD) and rheumatic …

Use of medications during pregnancy and breastfeeding for Crohn's disease and ulcerative colitis

R Laube, S Paramsothy, RW Leong - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction: The peak age of diagnosis of inflammatory bowel disease (IBD) occurs during
childbearing years, therefore management of IBD during pregnancy is a frequent …

Outcome of pregnancies in female patients with inflammatory bowel diseases treated with vedolizumab

A Moens, K van Hoeve, E Humblet… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background and Aims Vedolizumab is an IgG1 anti-α4β7 integrin antibody
approved for the treatment of inflammatory bowel diseases [IBD], but without clear safety …

Vedolizumab clearance in neonates, susceptibility to infections and developmental milestones: a prospective multicentre population‐based cohort study

M Julsgaard, DC Baumgart… - Alimentary …, 2021 - Wiley Online Library
Background Little is known about the consequences of intrauterine exposure to, and the
post‐natal clearance of, vedolizumab. Aims To investigate the levels of vedolizumab in …

Shared decision making in pregnancy in inflammatory bowel disease: design of a patient orientated decision aid

AJ Williams, N Karimi, R Chari, S Connor… - BMC …, 2021 - Springer
Background Research has indicated a lack of disease-specific reproductive knowledge
among patients with Inflammatory Bowel Disease (IBD) and this has been associated with …

Systematic review and meta‐analysis: Safety of vedolizumab during pregnancy in patients with inflammatory bowel disease

C Bell, P Tandon, E Lentz, JK Marshall… - Journal of …, 2021 - Wiley Online Library
Abstract Background and Aim Vedolizumab is a novel monoclonal antibody used in patients
with inflammatory bowel disease, often affecting women of child‐bearing age. We aimed to …