A test in context: D-dimer

JI Weitz, JC Fredenburgh, JW Eikelboom - Journal of the American College …, 2017 - jacc.org
D-dimer is a soluble fibrin degradation product that results from ordered breakdown of
thrombi by the fibrinolytic system. Numerous studies have shown that D-dimer serves as a …

Fibrinolysis and the control of blood coagulation

JC Chapin, KA Hajjar - Blood reviews, 2015 - Elsevier
Fibrin plays an essential role in hemostasis as both the primary product of the coagulation
cascade and the ultimate substrate for fibrinolysis. Fibrinolysis efficiency is greatly …

[HTML][HTML] Management of Deep Vein Thrombosis: An Update Based on the Revised AWMF S2k Guideline

B Linnemann, J Beyer-Westendorf… - …, 2024 - thieme-connect.com
Deep vein thrombosis (DVT) and pulmonary embolism (PE) are the most common
manifestations of venous thromboembolism (VTE). Most DVTs affect the lower-extremity …

Impact of D-dimer levels on admission on inhospital and long-term outcome in patients with type A acute aortic dissection

B Huang, Y Yang, H Lu, Z Zhao, S Zhang, R Hui… - The American journal of …, 2015 - Elsevier
Limited studies with relatively small sample sizes have reported that elevated d-dimer levels
on admission were associated with increased risk of short-term mortality in patients with type …

Effects of long-term high-altitude exposure on fibrinolytic system

P Jiang, Z Wang, X Yu, Y Qin, Y Shen, C Yang, F Liu… - …, 2021 - Taylor & Francis
Objective High altitude (HA), with the main feature of hypobaric hypoxia, is an independent
risk factor for thrombosis. However, little is known on the alterations of fibrinolytic system in …

[HTML][HTML] Evaluation of D‑dimer and lactate dehydrogenase plasma levels in patients with relapsed acute leukemia

W Hu, X Wang, R Yang - Oncology Letters, 2016 - spandidos-publications.com
Despite the outstanding advances made over the past decade regarding our knowledge of
acute leukemia (AL), relapsed AL remains to be associated with a dismal prognosis. A better …

Fibrin in nerve tissue engineering

J Heinzel, M Gloeckel, A Gruber, P Heher… - Peripheral Nerve Tissue …, 2022 - Springer
This chapter will focus on the use of fibrin for peripheral nerve repair and regeneration.
Important basic aspects of fibrinogen and fibrin will be summarized to elucidate the role of …

Fibrinolysis Index as a new predictor of deep vein thrombosis after traumatic lower extremity fractures

W Zhang, Y Su, L Liu, H Zhao, M Wen, Y Zhao, S Lu… - Clinica Chimica …, 2020 - Elsevier
Background Deep vein thrombosis (DVT) is a common complication in patients with
traumatic injury. The purpose of this study was to develop a potential predictor of DVT …

D-dimer is a predictor of 28-day mortality in critically ill patients receiving continuous renal replacement therapy

J Lu, X Wang, Q Chen, M Chen, L Cheng… - Archives of Medical …, 2016 - Elsevier
Background and Aims Continuous renal replacement therapy (CRRT) is an important
treatment in the intensive care unit (ICU). Nevertheless, the outcome of CRRT remains …

Diagnostic and prognostic value of the D-dimer test in emergency department patients: secondary analysis of an observational study

A Vögeli, M Ghasemi, C Gregoriano… - Clinical Chemistry and …, 2019 - degruyter.com
Background D-dimer measurement improves the rule-out of thromboembolic disease.
However, little is known about the risk of false positive results for the diagnosis of …