The self controlled case series (SCCS) method is an epidemiological study design for which
individuals act as their own control—ie, comparisons are made within individuals. Hence …

Purpose Consensus is needed on conceptual foundations, terminology and relationships
among the various self‐controlled “trigger” study designs that control for time‐invariant …

Background This study aims to evaluate the association between thromboembolic events
and hemorrhagic stroke following BNT162b2 and CoronaVac vaccination. Methods Patients …

Background & Aims Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs) and
low-dose aspirin increases the risk of upper gastrointestinal bleeding (UGIB). Guidelines …

Background. An association between infections and vascular events has been observed, but
the specific effect of influenza and influenza-like illnesses on triggering acute myocardial …

We propose a modified self‐controlled case series (SCCS) method to handle both event‐
dependent exposures and high event‐related mortality. This development is motivated by an …

Modern data linkage and technologies provide a way to reconstruct detailed longitudinal
profiles of health outcomes and predictors at the individual or small-area level. Although …

Aims/hypothesis Current drug labels for thiazolidinediones (TZDs) warn of increased
fractures, predominantly for distal fractures in women. We examined whether exposure to …

Self-Controlled Case Series Studies: A Modelling Guide with R provides the first
comprehensive account of the self-controlled case series (SCCS) method, a statistical …

Background Herpes zoster is common and can have serious consequences. Additionally,
emerging data suggest an increased risk of acute cardiovascular events following herpes …