[HTML][HTML] Molecular mechanism of the anti-inflammatory effects of plant essential oils: A systematic review

Q Zhao, L Zhu, S Wang, Y Gao, F Jin - Journal of ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Plant essential oils (PEOs) extracted from aromatic
compounds of the plant contain complex mixtures of volatile and lipophilic bioactive …

Frustration in biomolecules

DU Ferreiro, EA Komives, PG Wolynes - Quarterly reviews of …, 2014 - cambridge.org
Biomolecules are the prime information processing elements of living matter. Most of these
inanimate systems are polymers that compute their own structures and dynamics using as …

Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro

A Gritsenko, S Yu, F Martin-Sanchez… - Frontiers in …, 2020 - frontiersin.org
Interleukin (IL)-18 and IL-1β are potent pro-inflammatory cytokines that contribute to
inflammatory conditions such as rheumatoid arthritis and Alzheimer's disease. They are …

Lineage-restricted regulation of SCD and fatty acid saturation by MITF controls melanoma phenotypic plasticity

Y Vivas-García, P Falletta, J Liebing… - Molecular cell, 2020 - cell.com
Phenotypic and metabolic heterogeneity within tumors is a major barrier to effective cancer
therapy. How metabolism is implicated in specific phenotypes and whether lineage …

It takes two to tango: IκBs, the multifunctional partners of NF‐κB

M Hinz, SÇ Arslan, C Scheidereit - Immunological reviews, 2012 - Wiley Online Library
The inhibitory IκB proteins have been discovered as fundamental regulators of the inducible
transcription factor nuclear factor‐κB (NF‐κB). As a generally excepted model, stimulus …

Metabolic syndrome and skin diseases

Y Hu, Y Zhu, N Lian, M Chen, A Bartke… - Frontiers in …, 2019 - frontiersin.org
The increasing prevalence of Metabolic syndrome (MetS) is a worldwide health problem,
and the association between MetS and skin diseases has recently attracted growing …

Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioral, and …

E Guma, P do Couto Bordignon, GA Devenyi… - Biological …, 2021 - Elsevier
Background Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental disorders later in life. The impact of the gestational timing of MIA …

Fenofibrate downregulates NF-κB signaling to inhibit pro-inflammatory cytokine secretion in human THP-1 macrophages and during primary biliary cholangitis

GM Gallucci, B Alsuwayt, AM Auclair, JL Boyer… - Inflammation, 2022 - Springer
Chronic liver diseases, eg, cholestasis, are negatively impacted by inflammation, which
further aggravates liver injury. Pharmacotherapy targeting the peroxisome proliferator …

Angiotensin-converting enzyme 2 activator diminazene aceturate prevents lipopolysaccharide-induced inflammation by inhibiting MAPK and NF-κB pathways in …

L Tao, Y Qiu, X Fu, R Lin, C Lei, J Wang… - Journal of …, 2016 - Springer
Background Retinal inflammation is a devastating pathological process in ocular diseases.
Functional impairment of retinal pigment epithelium (RPE) is associated with inflammatory …

TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling

B Zhang, Z Zhang, L Li, YR Qin, H Liu, C Jiang… - Nature …, 2018 - nature.com
Beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC) is crucial for the
degradation of IκBα. Our previous transcriptome sequencing analysis revealed that …