Hyaluronic acid (HA) receptor CD44 is widely used for identifying cancer stem cells and its
activation promotes stemness. Recent evidence shows that overexpression of CD44 is …

Simple Summary Aptamers are versatile molecules for cancer treatment. They can be used
to target specific molecules, conjugated to additional nucleic acid moieties or payloads. In …

The phenomenon of T Cell exhaustion (TEX) entails a progressive deterioration in the
functionality of T cells within the immune system during prolonged conflicts with chronic …

Human cytomegalovirus (HCMV) infection has been implicated in epithelial ovarian cancer
(OC). Polyploidy giant cancer cells (PGCCs) have been observed in high-grade serous …

Breast cancer (BC) a very common cancer in women worldwide. Triple negative breast
cancer (TNBC) has been shown to have a poor prognosis with a high level of tumor …

Pancreatic ductal adenocarcinoma (PDAC) frequently metastasizes into the peritoneum,
which contributes to poor prognosis. Metastatic spreading is promoted by cancer cell …

Cancer stem cells (CSCs) may contribute to an increased risk of recurrence in ovarian
cancer (OC). Further research is needed to identify associations between CSC markers and …

Cisplatin (DDP) is the first-line chemotherapeutic agent for ovarian cancer. However, the
development of DDP resistance seriously influences the chemotherapeutic effect and …

Abstract Background Cancer stem cells (CSCs) are crucial for the growth, metastasis, drug
resistance, recurrence, and spread of tumors. Napabucasin (NAP) could effectively inhibit …

Ovarian cancer is a fatal gynecological malignancy. Although first-line chemotherapy and
surgical operation are effective treatments for ovarian cancer, its clinical management …