Signal amplification by reversible exchange (SABRE) is a rapidly developing nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …

Despite great successes in oncology, patient outcomes are often still discouraging, and
hence the diagnostic imaging paradigm is increasingly shifting toward functional imaging of …

Nuclear spin hyperpolarization enables real-time observation of metabolism and
intermolecular interactions in vivo. 1-13C-pyruvate is the leading hyperpolarized tracer …

Parahydrogen-induced polarisation (PHIP) is a nuclear spin hyperpolarisation technique
employed to enhance NMR signals for a wide range of molecules. This is achieved by …

Hyperpolarization modalities overcome the sensitivity limitations of NMR and unlock new
applications. Signal amplification by reversible exchange (SABRE) is a particularly cheap …

Para hydrogen (p-H2)-based techniques are known to drastically enhance NMR signals but
are usually limited by p-H2 supply. This work reports p-H2-based SABRE hyperpolarization …

The hydrogen molecule, which exists in two spin isomers (ortho‐and parahydrogen), is a
highly studied system due to its fundamental properties and practical applications …

The present work investigates the potential for enhancing the NMR signals of DNA
nucleobases by parahydrogen-based hyperpolarization. Signal amplification by reversible …

In recent years, parahydrogen‐induced hyperpolarization has become a focus for future
medical applications. Similar to the established dynamic nuclear polarization method, a …

Metal dihydride dihydrogen‐derived intermediates can be short‐lived and difficult to detect
despite their ubiquitous role in chemical transformations such as hydrogenation. Here …