Precision dosing priority criteria: drug, disease, and patient population variables

RJ Tyson, CC Park, JR Powell, JH Patterson… - Frontiers in …, 2020 - frontiersin.org
The administered dose of a drug modulates whether patients will experience optimal
effectiveness, toxicity including death, or no effect at all. Dosing is particularly important for …

Generic versus brand-name drugs used in cardiovascular diseases

L Manzoli, ME Flacco, S Boccia, E D'Andrea… - European journal of …, 2016 - Springer
This meta-analysis aimed to compare the efficacy and adverse events, either serious or
mild/moderate, of all generic versus brand-name cardiovascular medicines. We searched …

Variations in patients' perceptions and use of generic drugs: results of a national survey

AS Kesselheim, JJ Gagne, JM Franklin… - Journal of general …, 2016 - Springer
ABSTRACT BACKGROUND Over 84% of all prescriptions in the US are filled as generic
drugs, though in prior surveys, patients reported concerns about their quality. OBJECTIVE …

Improving adherence to therapy and clinical outcomes while containing costs: opportunities from the greater use of generic medications: best practice advice from the …

NK Choudhry, TD Denberg, A Qaseem… - Annals of internal …, 2016 - acpjournals.org
Description: The discrepancy between health care spending and achieved outcomes in the
United States has fueled efforts to identify and address situations where unnecessarily …

Generic medicines and generic substitution: contrasting perspectives of stakeholders in Ireland

A O'Leary, C Usher, M Lynch, M Hall, L Hemeryk… - BMC research …, 2015 - Springer
Abstract Background The Health (Pricing and Supply of Medical Goods) Act 2013 passed
into law in July 2013 and legislated for generic substitution in Ireland. The aim of the study …

Evaluation of blood pressure lowering effect by generic and brand-name antihypertensive drugs treatment: a multicenter prospective study in China

SY Zhang, LY Tao, YY Yang, T Kong, CJ Wu… - Chinese Medical …, 2021 - mednexus.org
Background: Generic drugs are bioequivalent to their brand-name counterparts; however,
concerns still exist regarding the effectiveness and safety of generic drugs because of small …

[HTML][HTML] Evaluation of rational prescribing in a hospital paediatric outpatient clinic in Nigeria

BI Okoye, JC Udemba, CA Ndugba… - BMJ paediatrics …, 2022 - ncbi.nlm.nih.gov
Background Irrational prescribing is a continuing public health issue in low/middle-income
countries. This study evaluated the drug use pattern of medicines in paediatrics aged below …

[PDF][PDF] Comparison between generic drugs and brand name drugs from bioequivalence and thermoequivalence prospective

M Arafat, Z Ahmed, O Arafat - Int. J. Pharm. Pharm. Sci, 2017 - academia.edu
The belief that generic drugs are inferior to brand name drugs has been always under
debate. Especially since the price of generic drugs is generally far cheaper than brand …

Deficiencies of the FDA in evaluating generic formulations: addressing narrow therapeutic index drugs

M Hottinger, BA Liang - American Journal of Law & Medicine, 2012 - cambridge.org
Generic drugs represent a significant portion of the medical arsenal in treating disease. As
copies of originator drugs, these drugs have been permitted abbreviated approval under the …

[HTML][HTML] Factors affecting the opinions of family physicians regarding generic drugs–a questionnaire based study

P Lewek, J Smigielski, P Kardas - Bosnian Journal of Basic …, 2015 - ncbi.nlm.nih.gov
A range of factors are believed to exert a negative influence on opinions of physicians about
generic drugs. The aim of this study was to survey the opinions of primary care doctors on …