Converting nanotoxicity data to information using artificial intelligence and simulation
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …
However, data is not equal to information. The question is how to extract critical information …
Understanding interactions between biomolecules and two-dimensional nanomaterials using in silico microscopes
Abstract Two-dimensional (2D) nanomaterials such as graphene are increasingly used in
research and industry for various biomedical applications. Extensive experimental and …
research and industry for various biomedical applications. Extensive experimental and …
Ultrathin 2D Titanium Carbide MXene (Ti3C2Tx) Nanoflakes Activate WNT/HIF‐1α‐Mediated Metabolism Reprogramming for Periodontal Regeneration
Periodontal defect regeneration in severe periodontitis relies on the differentiation and
proliferation of periodontal ligament cells (PDLCs). Recently, an emerging 2D nanomaterial …
proliferation of periodontal ligament cells (PDLCs). Recently, an emerging 2D nanomaterial …
Understanding the interactions between inorganic-based nanomaterials and biological membranes
Y Kang, J Liu, Y Jiang, S Yin, Z Huang, Y Zhang… - Advanced Drug Delivery …, 2021 - Elsevier
The interactions between inorganic-based nanomaterials (NMs) and biological membranes
are among the most important phenomena for developing NM-based therapeutics and …
are among the most important phenomena for developing NM-based therapeutics and …
Nanoparticles traversing the extracellular matrix induce biophysical perturbation of fibronectin depicted by surface chemistry
X Guo, L Yang, C Deng, L Ren, S Li, X Zhang, J Zhao… - Nanoscale, 2024 - pubs.rsc.org
While the filtering and accumulation effects of the extracellular matrix (ECM) on
nanoparticles (NPs) have been experimentally observed, the detailed interactions between …
nanoparticles (NPs) have been experimentally observed, the detailed interactions between …
The Inhibition of SARS-CoV-2 3CL Mpro by Graphene and Its Derivatives from Molecular Dynamics Simulations
J Wang, Y Yu, T Leng, Y Li, ST Lee - ACS Applied Materials & …, 2021 - ACS Publications
At present, the most powerful new drugs for COVID-19 are antibody proteins. In addition,
there are some star small molecule drugs. However, there are few studies on nanomaterials …
there are some star small molecule drugs. However, there are few studies on nanomaterials …
Effect of shape on the entering of graphene quantum dots into a membrane: a molecular dynamics simulation
Z Kong, P Zhang, J Chen, H Zhou, X Ma, H Wang… - ACS …, 2021 - ACS Publications
Graphene quantum dots (GQDs), a new quasi-zero-dimensional nanomaterial, have the
advantages of a smaller transverse size, better biocompatibility, and lower toxicity. They …
advantages of a smaller transverse size, better biocompatibility, and lower toxicity. They …
A mutagenesis study of autoantigen optimization for potential T1D vaccine design
A previously reported autoreactive antigen, termed the X-idiotype, isolated from a unique
cell population in Type 1 diabetes (T1D) patients, was found to stimulate their CD4+ T cells …
cell population in Type 1 diabetes (T1D) patients, was found to stimulate their CD4+ T cells …
Structural characterization of an intrinsically disordered protein complex using integrated small‐angle neutron scattering and computing
Characterizing structural ensembles of intrinsically disordered proteins (IDPs) and
intrinsically disordered regions (IDRs) of proteins is essential for studying structure–function …
intrinsically disordered regions (IDRs) of proteins is essential for studying structure–function …
How distinct structural flexibility within sars-cov-2 spike protein reveals potential therapeutic targets
The emergence and rapid worldwide spread of the novel coronavirus disease, COVID-19,
has prompted concerted efforts to find successful treatments. The causative virus, severe …
has prompted concerted efforts to find successful treatments. The causative virus, severe …