In the past decades there has been a dramatic increase in the demand for enantiopure
compounds for fine-chemicals (ie, agrochemicals and pharmaceuticals) and material …

The strong σ-donor but poor π-acceptor abilities of N-heterocyclic carbenes (NHCs) result in
chemical stability and coordination versatility, thus allowing them to coordinate with many …

This comprehensive reference and handbook covers in depth all major aspects of the use of
N-heterocyclic carbene-complexes in organic synthesis: from the theoretical background to …

Although the chemistry of copper has a long history [1a-d], the relatively recent discovery of
N-heterocyclic carbene (NHC) as transition-metal supporting ligands has permitted novel …

Efficient catalytic reactions that can generate C–C bonds enantioselectively, and ones that
can produce trisubstituted alkenes diastereoselectively, are central to research in organic …

A comprehensive overview of recent literature from 2003 concerning advances in
enantioselective copper catalysed 1, 4-addition of organometallic reagents to α, β …

Since the discovery of a stable “bottleable” N-heterocyclic carbene (NHC), there has been a
spectacular explosion of interest in this ligand class. This interest stems from a desire to …

N-Heterocyclic carbene ligated copper complexes act as catalysts in a variety of reactions. A
brief overview of this rich chemistry is given here. Of particular note is the ability of Cu (NHC) …

The copper-catalyzed asymmetric conjugate addition of Grignard reagents to trisubstituted
cyclic enones affords enantioenriched all-carbon quaternary centers with up to 96% ee. The …

The conjugate addition of carbon nucleophiles to acceptor activated olefins is one of the
most important reactions for carbon-carbon bond formation. With optically active metal …