Abstract Cystein-rich protein 61 (CYR61/CCN1) is a component of the extracellular matrix,
which is produced and secreted by several cell types including endothelial cells, fibroblasts …

The Yes‐associated protein (YAP)/Hippo pathway has been implicated in tissue
development, regeneration, and tumorigenesis. However, its role in cholangiocarcinoma …

Intrathymic T-cell differentiation is a key process for the development and maintenance of
cell-mediated immunity, and occurs concomitantly to highly regulated migratory events. We …

Accurate prediction of treatment response for cancer patients is essential for overcoming
intrinsic therapy resistance that results from genetic heterogeneity, varying tumor growth …

The thymus provides the physiological microenvironment critical for the development of T
lymphocytes, the cells that orchestrate the adaptive immune system to generate an antigen …

Inflammation is characterized by the recruitment of leukocytes from the bloodstream. The
rapid arrival of neutrophils is followed by a wave of inflammatory lymphocyte antigen 6 …

Thymic epithelial cells (TECs) form a 3-dimentional network supporting thymocyte
development and maturation. Besides epithelium and thymocytes, heterogeneous …

CCN1, an extracellular protein also known as cysteine-rich protein 61 (Cyr61), is a novel pro-
inflammatory factor involved in the pathogenesis of rheumatoid arthritis. As an inflammatory …

T cell development depends on sequential interactions of thymocytes with cortical thymic
epithelial cells (cTECs) and medullary thymic epithelial cells. PSMB11 is a catalytic …

Purpose Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is a chronic sinonasal
inflammatory disease characterized histologically by hyperplastic nasal epithelium and …