Detection of Bacillus anthracis in the field, whether as a natural infection or as a biothreat
remains challenging. Here we have developed a new lateral-flow immunochromatographic …

Bacterial lysis is a critical step in bioassays and serves as a pretreatment to extract genomic
material before various genomic bioassays. These assays are used for microbial profiling …

For indirect DNA extraction for metagenomics studies, bacterial cells can be effectively
separated from sample debris by using a simple size exclusion technique, such as filtration …

Detecting pathogenic bacteria in food or other biological samples with lab-on-a-chip (LOC)
devices requires several sample preparation steps prior to analysis which commonly …

Identifying virulent Bacillus anthracis within soil is a difficult task due to the number and
diversity of other organisms and impeding chemical constituents within soil. Regardless of …

DNA hybridization phenomena occurring on solid supports are not understood as clearly as
aqueous phase hybridizations and mathematical models cannot predict some empirically …

This paper describes the design, functioning and use of a portable detection platform for
multiplex nucleic acid testing. The system features a bead-supported DNA hybridization …

As part of investigative sampling there is a need to rapidly concentrate the target from large
sample volumes to enable downstream detection using suitable diagnostic platforms. To this …

Decontamination of suspected packages, such as sealed envelopes, liquids and tools that
are likely contaminated with biological agents is of great importance. In this study, we aimed …

Automated methods for rapidly purifying and concentrating bacteria from environmental
interferents are needed in next-generation applications for anything from water purification …