Are COVID-19 vaccine boosters needed? The science behind boosters
Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants
has led to increases in breakthrough infections, prompting consideration for vaccine booster …
has led to increases in breakthrough infections, prompting consideration for vaccine booster …
Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination
Abstract SARS-CoV-2 Delta and Omicron are globally relevant variants of concern. Although
individuals infected with Delta are at risk of developing severe lung disease, infection with …
individuals infected with Delta are at risk of developing severe lung disease, infection with …
Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors
L Pérez-Alós, JJA Armenteros, JR Madsen… - Nature …, 2022 - nature.com
SARS-CoV-2 vaccines are crucial in controlling COVID-19, but knowledge of which factors
determine waning immunity is limited. We examined antibody levels and T-cell gamma …
determine waning immunity is limited. We examined antibody levels and T-cell gamma …
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
COVID-19 vaccine–related myocardial and pericardial inflammation
Abstract Purpose of Review To review myocarditis and pericarditis developing after COVID-
19 vaccinations and identify the management strategies. Recent Findings COVID-19 mRNA …
19 vaccinations and identify the management strategies. Recent Findings COVID-19 mRNA …
ImmunosuppressiveTherapies differently modulate Humoral-and T-cell-specific responses to COVID-19 mRNA vaccine in rheumatoid arthritis patients
Objective To assess in rheumatoid arthritis (RA) patients, treated with different
immunosuppressive therapies, the induction of SARS-CoV-2-specific immune response …
immunosuppressive therapies, the induction of SARS-CoV-2-specific immune response …
COVID-19 delta variant: perceptions, worries, and vaccine-booster acceptability among healthcare workers
Background: As the COVID-19 Delta variant has spread across the globe, healthcare
workers'(HCWs) knowledge, worries, and vaccine booster acceptance should be assessed …
workers'(HCWs) knowledge, worries, and vaccine booster acceptance should be assessed …
SARS-CoV-2 spike-specific CD4+ T cell response is conserved against variants of concern, including omicron
Although accumulating data have investigated the effect of SARS-CoV-2 mutations on
antibody neutralizing activity, less is known about T cell immunity. In this work, we found that …
antibody neutralizing activity, less is known about T cell immunity. In this work, we found that …
Oral delivery of mRNA vaccine by plant-derived extracellular vesicle carriers
MAC Pomatto, C Gai, F Negro, L Massari… - Cells, 2023 - mdpi.com
mRNA-based vaccines were effective in contrasting SARS-CoV-2 infection. However, they
presented several limitations of storage and supply chain, and their parenteral …
presented several limitations of storage and supply chain, and their parenteral …
Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines
Despite the successes of current coronavirus disease 2019 (COVID-19) vaccines, waning
immunity, the emergence of variants of concern, and breakthrough infections among …
immunity, the emergence of variants of concern, and breakthrough infections among …