Many bacteria use CRISPR–Cas systems to combat mobile genetic elements, such as
bacteriophages and plasmids. In turn, these invasive elements have evolved anti-CRISPR …

Vaborbactam (formerly RPX7009) is a new beta-lactamase inhibitor based on a cyclic
boronic acid pharmacophore. The spectrum of beta-lactamase inhibition by vaborbactam …

Abstract The 'Standard European Vector Architecture'database (SEVA-DB, http://seva. cnb.
csic. es) was conceived as a user-friendly, web-based resource and a material clone …

Bacteria become highly tolerant to antibiotics when nutrients are limited. The inactivity of
antibiotic targets caused by starvation-induced growth arrest is thought to be a key …

Bacteria assume distinct lifestyles during the planktonic and biofilm modes of growth.
Increased levels of the intracellular messenger c-di-GMP determine the transition from …

Mutation-dependent overproduction of intrinsic β-lactamase AmpC is considered the main
cause of resistance of clinical strains of Pseudomonas aeruginosa to antipseudomonal …

Numerous species of bacteria use an elegant regulatory mechanism known as quorum
sensing to control the expression of specific genes in a cell-density dependent manner. In …

A rapid microcentrifuge-based method is described for preparation of Pseudomonas
aeruginosa electrocompetent cells with up to 10,000-fold increased transformation …

Novel molecular tools have been constructed which allow for in situ detection of N-acyl
homoserine lactone (AHL)-mediated quorum sensing in Pseudomonas aeruginosa biofilms …

Two seven-gene phenazine biosynthetic loci were cloned from Pseudomonas aeruginosa
PAO1. The operons, designated phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2, are …