Transposons populate the landscape of all eukaryotic genomes. Often considered purely
genomic parasites, transposons can also benefit their hosts, playing roles in gene regulation …

Ciliated protozoa undergo large-scale developmental rearrangement of their somatic
genomes when forming a new transcriptionally active macronucleus during conjugation …

In animal germlines, transposons are silenced at the transcriptional or post-transcriptional
level to prevent deleterious expression. Ciliates employ a more direct approach by …

Programmed genome rearrangements drive functional gene assembly in ciliates during the
development of the somatic macronucleus. The elimination of germline sequences is …

Genome stability is a crucial feature of eukaryotic organisms because its alteration
drastically affects the normal development and survival of cells and the organism as a …

Genome duality in ciliated protozoa offers a unique system to showcase their epigenome as
a model of inheritance. In Oxytricha, the somatic genome is responsible for vegetative …

Insertions of parasitic DNA within coding sequences are usually deleterious and are
generally counter-selected during evolution. Thanks to nuclear dimorphism, ciliates provide …

Ciliates are a highly divergent group of unicellular eukaryotes with separate somatic and
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …

Research using ciliates revealed early examples of epigenetic phenomena and continues to
provide novel findings. These protozoans maintain separate germline and somatic nuclei …

Ciliated protozoa extensively remodel their somatic genomes during nuclear development,
fragmenting their chromosomes and removing large numbers of internal eliminated …