Cognitive impact of COVID-19: looking beyond the short term

S Miners, PG Kehoe, S Love - Alzheimer's research & therapy, 2020 - Springer
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …

Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology

SJ Forrester, GW Booz, CD Sigmund… - Physiological …, 2018 - journals.physiology.org
The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …

Nicotine and the renin-angiotensin system

JM Oakes, RM Fuchs, JD Gardner… - American Journal …, 2018 - journals.physiology.org
Cigarette smoking is the single most important risk factor for the development of
cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in …

Hypertension: renin–angiotensin–aldosterone system alterations

L Te Riet, JHM van Esch, AJM Roks… - Circulation …, 2015 - Am Heart Assoc
Blockers of the renin–angiotensin–aldosterone system (RAAS), that is, renin inhibitors,
angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists …

AT1 receptor signaling pathways in the cardiovascular system

T Kawai, SJ Forrester, S O'Brien, A Baggett… - Pharmacological …, 2017 - Elsevier
The importance of the renin angiotensin aldosterone system in cardiovascular physiology
and pathophysiology has been well described whereas the detailed molecular mechanisms …

ACE2/ANG-(1–7)/Mas pathway in the brain: the axis of good

P Xu, S Sriramula… - American Journal of …, 2011 - journals.physiology.org
The last decade has seen the discovery of several new components of the renin-angiotensin
system (RAS). Among them, angiotensin converting enzyme-2 (ACE2) and the Mas receptor …

[HTML][HTML] Many faces of renin-angiotensin system-focus on eye

M Holappa, H Vapaatalo… - The open ophthalmology …, 2017 - ncbi.nlm.nih.gov
The renin-angiotensin system (RAS), that is known for its role in the regulation of blood
pressure as well as in fluid and electrolyte homeostasis, comprises dozens of angiotensin …

Update on the angiotensin converting enzyme 2-angiotensin (1–7)-Mas receptor axis: fetal programing, sex differences, and intracellular pathways

MC Chappell, AC Marshall, EM Alzayadneh… - Frontiers in …, 2014 - frontiersin.org
The renin-angiotensin-system (RAS) constitutes an important hormonal system in the
physiological regulation of blood pressure. Indeed, dysregulation of the RAS may lead to the …

Recent advances in the health benefits of pea protein (Pisum sativum): Bioactive peptides and the interaction with the gut microbiome

J Wang, S Kadyan, V Ukhanov, J Cheng… - Current Opinion in Food …, 2022 - Elsevier
Plant-based protein products, either as a protein supplement or food ingredient, have
gained increasing consumer attention and interest owing to their 'organic'green nature and …

Role of the renin–angiotensin–aldosterone and kinin–kallikrein systems in the cardiovascular complications of COVID-19 and long COVID

SL Cooper, E Boyle, SR Jefferson, CRA Heslop… - International Journal of …, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus responsible
for the COVID-19 pandemic. Patients may present as asymptomatic or demonstrate mild to …