S100B is a Ca2+‐binding protein mainly concentrated in astrocytes. Its levels in biological
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …

Early or primary injury due to brain aggression, such as mechanical trauma, hemorrhage or
is-chemia, triggers the release of damage-associated molecular patterns (DAMPs) in the …

Aneurysmal subarachnoid hemorrhage (aSAH) represents only a small portion of all strokes,
but accounts for almost half of the deaths caused by stroke worldwide. Neurosurgical …

In 1989, Janeway (1) introduced a conceptual framework to understand how the innate
immune system selectively responds to potentially threatening infections. Based on …

Neurological disorders pose a great threat to social health and are a major cause for
mortality and morbidity. Effective drug development complemented with the improved drug …

After subarachnoid haemorrhage, prolonged exposure to toxic extracellular haemoglobin
occurs in the brain. Here, we investigate the role of haemoglobin neurotoxicity in vivo and its …

Recently, growing attention has been paid to the changes of brain biomarkers following the
epilepsy. However, establishing specific epilepsy-related biomarkers has been impeded …

Background Calcium-binding proteins are heterogeneous proteins that act binding this ion
in specific domains, performing numerous functions. Objective In the present review, we aim …

miRNAs are important regulators of translation and have been associated with the
pathogenesis of a number of cardiovascular diseases including stroke and may be possible …

Objectives The study of biomarkers related to the infarct volume of acute ischaemic stroke
(AIS) is a valuable clinical strategy. We conducted a prospective study to evaluate the …