Comorbid depression in medical diseases

SM Gold, O Köhler-Forsberg, R Moss-Morris… - Nature Reviews …, 2020 - nature.com
Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

The role of inflammation in depression and fatigue

CH Lee, F Giuliani - Frontiers in immunology, 2019 - frontiersin.org
Depression and fatigue are conditions responsible for heavy global societal burden,
especially in patients already suffering from chronic diseases. These symptoms have been …

The link between depression and diabetes: the search for shared mechanisms

CD Moulton, JC Pickup, K Ismail - The lancet Diabetes & …, 2015 - thelancet.com
Depression is twice as common in people with type 1 or type 2 diabetes as in the general
population, and is associated with poor outcomes. Evidence is growing that depression and …

Longitudinal associations between depression and diabetes complications: a systematic review and meta‐analysis

A Nouwen, MC Adriaanse, K van Dam… - Diabetic …, 2019 - Wiley Online Library
To conduct a systematic review and meta‐analysis of longitudinal studies assessing the bi‐
directional association between depression and diabetes macrovascular and microvascular …

Chemokines in depression in health and in inflammatory illness: a systematic review and meta-analysis

SP Leighton, L Nerurkar, R Krishnadas… - Molecular …, 2018 - nature.com
Inflammatory illness is associated with depression. Preclinical work has shown that
chemokines are linked with peripheral–central crosstalk and may be important in mediating …

Treatment for comorbid depressive disorder or subthreshold depression in diabetes mellitus: Systematic review and meta‐analysis

C van der Feltz‐Cornelis, SF Allen, RIG Holt… - Brain and …, 2021 - Wiley Online Library
Objective To provide an estimate of the effect of interventions on comorbid depressive
disorder (MDD) or subthreshold depression in type 1 and type 2 diabetes. Methods …

Depression in people with type 2 diabetes: current perspectives

L Darwish, E Beroncal, MV Sison… - … syndrome and obesity …, 2018 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is associated with depressive symptoms, and comorbid
depression in those with T2DM has been associated with adverse clinical profiles …

Metformin ameliorates stress-induced depression-like behaviors via enhancing the expression of BDNF by activating AMPK/CREB-mediated histone acetylation

W Fang, J Zhang, L Hong, W Huang, X Dai, Q Ye… - Journal of affective …, 2020 - Elsevier
Background Metformin, a first-line antiglycemic drug, has been reported to have anti-
depressant effects in patients with type 2 diabetes; however, its exact role and underlying …

[HTML][HTML] Psychological aspects of diabetes care: Effecting behavioral change in patients

BH Chew, S Shariff-Ghazali… - World journal of …, 2014 - ncbi.nlm.nih.gov
Patients with diabetes mellitus (DM) need psychological support throughout their life span
from the time of diagnosis. The psychological make-up of the patients with DM play a central …

Diversity and plasticity of microglial cells in psychiatric and neurological disorders

Y Nakagawa, K Chiba - Pharmacology & therapeutics, 2015 - Elsevier
Recent advanced immunological analyses have revealed that the diversity and plasticity of
macrophages lead to the identification of functional polarization states (classically activated …