High-dose of vitamin C (L-ascorbic acid, ascorbate) exhibits anti-tumoral effects, primarily
mediated by pro-oxidant mechanisms. This cytotoxic effect is thought to affect the reciprocal …

Introduction: DICER1 is a member of RNase III family that has a pivotal role in the
biogenesis of microRNAs, being important for normal development. Dysregulation of …

Initiation of epithelial-to-mesenchymal transition (EMT) is common in papillary thyroid
carcinoma (PTC) and may contribute to its metastasis. Aims of the present study are to …

In order to better understand the mechanisms underlying the development of papillary
thyroid carcinoma (PTC), and to identify new potential biomarkers, high-resolution label-free …

Abstract Introduction In Colombia, thyroid cancer ranks among the highest incidences, yet
our population lacks studies on its molecular profile. This study aims to characterize clinical …

Papillary thyroid microcarcinoma (PTMC) is defined by the World Health Organization as
papillary cancer measuring 10 mm or less in diameter. Generally, PTMC shows an indolent …

Background Recognizing aggressive tumor biology is essential to optimizing patient
management for papillary thyroid carcinomas (PTC). Aggressive lymph node (ALN) status is …

Background/Aim: Mammalian target of rapamycin (mTOR) plays an important role in
papillary thyroid carcinoma (PTC) cell progression. CZ415 is a novel, highly-efficient and …

Background CXC motif chemokine ligand 5 (CXCL5) is a chemokine molecule that is
secreted by immune cells in attracting granulocytes. Studies showed that CXCL5 was …

Simple Summary Although papillary thyroid carcinoma (PTC) is generally a highly curable
disease, there is a small subgroup of PTC cases that behaves more aggressively, with high …