[HTML][HTML] A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

[PDF][PDF] Large-scale analyses of human microbiomes reveal thousands of small, novel genes

H Sberro, BJ Fremin, S Zlitni, F Edfors, N Greenfield… - Cell, 2019 - cell.com
Small proteins are traditionally overlooked due to computational and experimental
difficulties in detecting them. To systematically identify small proteins, we carried out a …

Small proteins encoded by unannotated ORFs are rising stars of the proteome, confirming shortcomings in genome annotations and current vision of an mRNA

V Delcourt, A Staskevicius, M Salzet, I Fournier… - …, 2018 - Wiley Online Library
Short ORF‐encoded peptides and small proteins in eukaryotes have been hiding in the
shadow of large proteins for a long time. Recently, improved identifications in MS‐based …

[PDF][PDF] Thousands of small, novel genes predicted in global phage genomes

BJ Fremin, AS Bhatt, NC Kyrpides, A Sengupta… - Cell reports, 2022 - cell.com
Summary Small genes (< 150 nucleotides) have been systematically overlooked in phage
genomes. We employ a large-scale comparative genomics approach to predict> 40,000 …

No one tool to rule them all: prokaryotic gene prediction tool annotations are highly dependent on the organism of study

NJ Dimonaco, W Aubrey, K Kenobi, A Clare… - …, 2022 - academic.oup.com
Abstract Motivation The biases in CoDing Sequence (CDS) prediction tools, which have
been based on historic genomic annotations from model organisms, impact our …

[HTML][HTML] Protein length distribution is remarkably uniform across the tree of life

Y Nevers, NM Glover, C Dessimoz, O Lecompte - Genome Biology, 2023 - Springer
Background In every living species, the function of a protein depends on its organization of
structural domains, and the length of a protein is a direct reflection of this. Because every …

SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci

Y Hao, L Zhang, Y Niu, T Cai, J Luo, S He… - Briefings in …, 2018 - academic.oup.com
Small proteins is the general term for proteins with length shorter than 100 amino acids.
Identification and functional studies of small proteins have advanced rapidly in recent years …

[HTML][HTML] Genome-wide identification of transcriptional start sites in the haloarchaeon Haloferax volcanii based on differential RNA-Seq (dRNA-Seq)

J Babski, KA Haas, D Näther-Schindler, F Pfeiffer… - BMC genomics, 2016 - Springer
Abstract Background Differential RNA-Seq (dRNA-Seq) is a recently developed method of
performing primary transcriptome analyses that allows for the genome-wide mapping of …

A metabolic pathway for catabolizing levulinic acid in bacteria

JM Rand, T Pisithkul, RL Clark, JM Thiede… - Nature …, 2017 - nature.com
Microorganisms can catabolize a wide range of organic compounds and therefore have the
potential to perform many industrially relevant bioconversions. One barrier to realizing the …

[HTML][HTML] The molecular mass and isoelectric point of plant proteomes

TK Mohanta, A Khan, A Hashem, EF Abd_Allah… - BMC genomics, 2019 - Springer
Background Cell contain diverse array of proteins with different molecular weight and
isoelectric point (pI). The molecular weight and pI of protein play important role in …