The tumor microenvironment (TME) is a complex and ever-changing “rogue organ”
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …

Mesenchymal stem cells (MSCs) derived from adipose tissue, bone marrow, cord blood, and
other tissues, have recently attracted much attention as potential therapeutic agents in …

The anti-tumor activities of some members of the chemokine family are often overcome by
the functions of many chemokines that are strongly and causatively linked with increased …

For decades tumors have been recognized as “wounds that do not heal.” Besides the
commonalities that tumors and wounded tissues share, the process of wound healing also …

The interactions between tumor cells and the non-malignant stromal and immune cells that
make up the tumor microenvironment (TME) are critical to the pathophysiology of cancer …

Mesenchymal stem cells (MSCs) are multipotent progenitor cells that participate in the
structural and functional maintenance of connective tissues under normal homeostasis …

Epithelial to mesenchymal transition (EMT) involves loss of an epithelial phenotype and
activation of a mesenchymal one. Enhanced expression of genes associated with a …

Mammary adipose tissue (AT) is necessary for breast epithelium. However, in breast cancer
(BC), cell-cell interactions are deregulated as the tumor chronically modifies AT …

Gastric cancer is the fourth most common cause of cancer-linked deaths in the world. Gastric
tumor cells have biological characteristics such as rapid proliferation, high invasiveness …

Over the past few decades, longevity without disease has become an important topic
worldwide. However, as life expectancy increases, the number of patients with cancer is also …