Dietary phenolic compounds: their health benefits and association with the gut microbiota

Y Matsumura, M Kitabatake, S Kayano, T Ito - Antioxidants, 2023 - mdpi.com
Oxidative stress causes various diseases, such as type II diabetes and dyslipidemia, while
antioxidants in foods may prevent a number of diseases and delay aging by exerting their …

Isoflavones derived from plant raw materials: Bioavailability, anti-cancer, anti-aging potentials, and microbiome modulation

SA Aboushanab, SM Khedr, IF Gette… - Critical Reviews in …, 2022 - Taylor & Francis
Isoflavones are secondary metabolites that represent the most abundant category of plant
polyphenols. Dietary soy, kudzu, and red clover contain primarily genistein, daidzein …

Isoflavone diet ameliorates experimental autoimmune encephalomyelitis through modulation of gut bacteria depleted in patients with multiple sclerosis

SN Jensen, NM Cady, SK Shahi, SR Peterson… - Science …, 2021 - science.org
The gut microbiota is a potential environmental factor that influences the development of
multiple sclerosis (MS). We and others have demonstrated that patients with MS and healthy …

Dietary plant polyphenols as the potential drugs in neurodegenerative diseases: current evidence, advances, and opportunities

L Yan, MS Guo, Y Zhang, L Yu, JM Wu… - Oxidative Medicine …, 2022 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …

An oriental medicine, Hyungbangpaedok-San attenuates motor paralysis in an experimental model of multiple sclerosis by regulating the T cell response

JH Choi, MJ Lee, M Jang, EJ Kim, I Shim, HJ Kim… - PloS one, 2015 - journals.plos.org
The preventive and therapeutic mechanisms in multiple sclerosis are not clearly understood.
We investigated whether Hyungbangpaedok-san (HBPDS), a traditional herbal medicine …

Molecular mechanisms underlying the potential neuroprotective effects of Trifolium pratense and its phytoestrogen‐isoflavones in neurodegenerative disorders

AS Al‐Shami, AE Essawy… - Phytotherapy …, 2023 - Wiley Online Library
Neurodegenerative disorders are heterogeneous, debilitating, and incurable groups of brain
disorders that have common features including progressive degeneration of the structure …

Risks and benefits related to alimentary exposure to xenoestrogens

I Paterni, C Granchi, F Minutolo - Critical reviews in food science …, 2017 - Taylor & Francis
Xenoestrogens are widely diffused in the environment and in food, thus a large portion of
human population worldwide is exposed to them. Among alimentary xenoestrogens …

[HTML][HTML] An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone …

N Zhang, L Jin, C Liu, R Zhang, HC Siebert, Y Li… - Journal of Functional …, 2021 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous
system, and results in the degradation of the myelin sheath. The study investigates the …

Cuprizone-induced demyelination in the mouse hippocampus is alleviated by phytoestrogen genistein

T Ohgomori, S Jinno - Toxicology and applied pharmacology, 2019 - Elsevier
One of the major female sex hormones, estrogen, can influence a variety of mental states.
Individuals with multiple sclerosis (MS) often suffer from mental health issues, which are …

Effect of endocrine disruptor phytoestrogens on the immune system: Present and future

G Csaba - Acta Microbiologica et Immunologica Hungarica, 2018 - akjournals.com
Endocrine disruptors (EDs) are bound by steroid receptors, have steroid-like effects, and by
this, negatively influence hormone-regulated processes. Phytoestrogens, which are …