Toolbox for distal C–H bond functionalizations in organic molecules

SK Sinha, S Guin, S Maiti, JP Biswas, S Porey… - Chemical …, 2021 - ACS Publications
Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Visible‐light photocatalysis: does it make a difference in organic synthesis?

L Marzo, SK Pagire, O Reiser… - Angewandte Chemie …, 2018 - Wiley Online Library
Visible‐light photocatalysis has evolved over the last decade into a widely used method in
organic synthesis. Photocatalytic variants have been reported for many important …

Controlling Ni redox states by dynamic ligand exchange for electroreductive Csp3–Csp2 coupling

TB Hamby, MJ LaLama, CS Sevov - Science, 2022 - science.org
Cross-electrophile coupling (XEC) reactions of aryl and alkyl electrophiles are appealing but
limited to specific substrate classes. Here, we report electroreductive XEC of previously …

Controlling Reactivity and Selectivity in the Nondirected C–H Activation of Arenes with Palladium

S Kaltenberger, M van Gemmeren - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Aromatic structures are widespread motifs throughout organic chemistry, and C–
H activation has been recognized as a major tool for enabling their sustainable and efficient …

Modern transition-metal-catalyzed carbon–halogen bond formation

DA Petrone, J Ye, M Lautens - Chemical Reviews, 2016 - ACS Publications
The high utility of halogenated organic compounds has prompted the development of a vast
number of transformations which install the carbon–halogen motif. Traditional routes to …

Photokatalyse mit sichtbarem Licht: Welche Bedeutung hat sie für die organische Synthese?

L Marzo, SK Pagire, O Reiser, B König - Angewandte Chemie, 2018 - Wiley Online Library
Abstract Die Photokatalyse mit sichtbarem Licht hat sich im letzten Jahrzehnt zu einer breit
angewandten Methode in der organischen Synthese entwickelt. Für viele wichtige …

Beyond Directing Groups: Transition‐Metal‐Catalyzed C H Activation of Simple Arenes

N Kuhl, MN Hopkinson… - Angewandte Chemie …, 2012 - Wiley Online Library
The use of coordinating moieties as directing groups for the functionalization of aromatic C
H bonds has become an established tool to enhance reactivity and induce regioselectivity …

DMSO-catalysed late-stage chlorination of (hetero) arenes

S Song, X Li, J Wei, W Wang, Y Zhang, L Ai, Y Zhu… - Nature Catalysis, 2020 - nature.com
The chlorination of a bioactive compound can change its physiological properties and
improve its pharmacokinetic and pharmacological profiles. It therefore has been an …

Arene‐Limited Nondirected C− H Activation of Arenes

P Wedi, M van Gemmeren - Angewandte Chemie International …, 2018 - Wiley Online Library
Abstract The nondirected C (sp2)− H activation of simple arenes has advanced significantly
in recent years through the discovery of new catalyst systems that are able to perform …

Ohne dirigierende gruppen: übergangsmetallkatalysierte C‐H‐Aktivierung einfacher Arene

N Kuhl, MN Hopkinson, J Wencel‐Delord… - Angewandte …, 2012 - Wiley Online Library
Abstract Der Einsatz von koordinierenden Gruppen als dirigierende Gruppen ist eine
zuverlässige Methode zur Kontrolle von Reaktivität und Selektivität bei der Aktivierung von …