Toll-like receptors play a vital role in cell-mediated immunity, which is crucial for the immune
system's defense against pathogens and maintenance of homeostasis. The interaction …

Osteosarcoma, a malignant bone tumor predominantly affecting children and adolescents,
presents significant therapeutic challenges, particularly in metastatic or recurrent cases …

Simple Summary Due to the lack of progress in OsA's treatment and survival, there is a need
to develop new therapeutic approaches for this tumor. OsA is a complex tumor for which the …

Dendritic cells (DCs) are involved in the initiation and maintenance of immune responses
against malignant cells by recognizing conserved pathogen-associated molecular patterns …

Objective: Studies have firmly established the pivotal role of the immunogenic cell death
(ICD) in the development of tumors. This study seeks to develop a risk model related to ICD …

Infectious diseases are a predominant problem in human health. While the incidence of
many pathogenic infections is controlled by vaccines, some pathogens still pose a …

Understanding the intricacies of the metabolic phenotype in immune cells and its plasticity
within the tumor microenvironment is pivotal in understanding the pathology and prognosis …

Osteosarcoma treatment comprises pre-surgical chemotherapy followed by radical surgery
and further chemotherapy cycles, but the prognosis has been far from satisfactory. No new …

Osteosarcoma (OSA) is the most common cancer of the bone and third most common cancer
diagnosed in children and adolescent. The five-year survival rate for OSA patients …