Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease–novel insights into cellular communication circuits
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease and is
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …
[PDF][PDF] Pathogenesis of nonalcoholic steatohepatitis: an overview
G Parthasarathy, X Revelo… - Hepatology …, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous group of liver diseases
characterized by the accumulation of fat in the liver. The heterogeneity of NAFLD is reflected …
characterized by the accumulation of fat in the liver. The heterogeneity of NAFLD is reflected …
Triggering and resolution of inflammation in NASH
S Schuster, D Cabrera, M Arrese… - Nature reviews …, 2018 - nature.com
Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
[HTML][HTML] Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms
CN Serhan - The FASEB Journal, 2017 - ncbi.nlm.nih.gov
Practitioners of ancient societies from the time of Hippocrates and earlier recognized and
treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or …
treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or …
[HTML][HTML] Oxidative stress and non-alcoholic fatty liver disease: effects of omega-3 fatty acid supplementation
J Yang, M Fernández-Galilea, L Martínez-Fernández… - Nutrients, 2019 - mdpi.com
Aging is a complex phenomenon characterized by the progressive loss of tissue and organ
function. The oxidative-stress theory of aging postulates that age-associated functional …
function. The oxidative-stress theory of aging postulates that age-associated functional …
Bioactive lipid species and metabolic pathways in progression and resolution of nonalcoholic steatohepatitis
G Musso, M Cassader, E Paschetta, R Gambino - Gastroenterology, 2018 - Elsevier
The prevalence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, yet there
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …
[HTML][HTML] Treating inflammation to combat non-alcoholic fatty liver disease
L Wiering, F Tacke - Journal of Endocrinology, 2023 - joe.bioscientifica.com
Non-alcoholic fatty liver disease (NAFLD) with its more progressive form non-alcoholic
steatohepatitis (NASH) has become the most common chronic liver disease, thereby …
steatohepatitis (NASH) has become the most common chronic liver disease, thereby …
Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies
G Musso, M Cassader, R Gambino - Nature reviews Drug discovery, 2016 - nature.com
Non-alcoholic fatty liver disease—the most common chronic liver disease—encompasses a
histological spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) …
histological spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) …
Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors
The acute inflammatory response is host-protective to contain foreign invaders. Many of
today's pharmacopeia that block pro-inflammatory chemical mediators can cause serious …
today's pharmacopeia that block pro-inflammatory chemical mediators can cause serious …
Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function
Unresolved inflammation is a major contributor to the development of heart failure following
myocardial infarction (MI). Pro-resolving lipid mediators, such as resolvins (eg RvD1), are …
myocardial infarction (MI). Pro-resolving lipid mediators, such as resolvins (eg RvD1), are …