Photodynamic therapy (PDT) utilizes the destructive power of reactive oxygen species
generated via visible light irradiation of a photosensitive dye accumulated in the cancerous …

The “holy grail” of cancer therapy is to identify and exploit genetic elements and signal
transduction pathways capable of selectively destroying tumor cells without eliciting harmful …

First identified almost two decades ago as a novel gene differentially expressed in human
melanoma cells induced to terminally differentiate, MDA-7/IL-24 has since shown great …

IL-24 is a member of the IL-10 family of cytokines. In this study, we investigated IL-24
expression in the inflamed mucosa of patients with inflammatory bowel disease (IBD), and …

Apoptosis and autophagy play seminal roles in maintaining organ homeostasis. Apoptosis
represents canonical type I programmed cell death. Autophagy is viewed as pro-survival …

Abstract IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29 are new members of the IL-10
interferon family. Monocytes are well-known sources of IL-19, IL-20, and IL-24. We …

Tumor progression and metastasis are complex processes involving intricate interplay
among multiple gene products. Astrocyte elevated gene (AEG)-1 was cloned as an human …

A noteworthy aspect of melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-
24) as a cancer therapeutic is its ability to selectively kill cancer cells without harming normal …

Melanoma differentiation-associated gene 7 (mda-7)/interleukin-24 (IL-24) is a unique
member of the IL-10 gene family, which displays a broad range of antitumor properties …

Abstract Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) is a
unique member of the IL-10 gene family that induces cancer-selective growth suppression …