Metastasis is a complex, multistep process responsible for> 90% of cancer-related deaths. In
addition to genetic and external environmental factors, the physical interactions of cancer …

The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the
inside of the nuclear membrane, where they provide a platform for the binding of proteins …

The nuclear envelope defines the barrier between the nucleus and cytoplasm and features
inner and outer membranes separated by a perinuclear space (PNS). The inner nuclear …

The cereal endosperm is a major factor determining seed size and shape. However, the
molecular mechanisms of endosperm development are not fully understood. Long …

The nuclear envelope links the cytoskeleton to structural components of the nucleus. It
functions to coordinate nuclear migration and anchorage, organize chromatin, and aid …

Many nuclear proteins form lamin-dependent complexes, including LEM-domain proteins,
nesprins and SUN-domain proteins. These complexes have roles in chromatin organization …

The nuclear envelope (NE) is a highly regulated membrane barrier that separates the
nucleus from the cytoplasm in eukaryotic cells. It contains a large number of different …

Emery–Dreifuss muscular dystrophy (EDMD) is a heterogeneous late-onset disease
involving skeletal muscle wasting and heart defects caused, in a minority of cases, by …

The microtubule-organizing center (MTOC) is reoriented between the nucleus and the
leading edge in many migrating cells and contributes to directional migration. Models …

Nuclear migration and positioning within cells are critical for many developmental processes
and are governed by the cytoskeletal network. Although mechanisms of nuclear-cytoskeletal …