Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids
Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …
aroused great interest in medicinal chemists for the development of new drugs or drug …
Xanthomonas citri subsp. citri: host interaction and control strategies
PMM Martins, M de Oliveira Andrade… - Tropical Plant …, 2020 - Springer
Citrus is one of the most ancient fruit crops cultivated in the world. For many countries, citrus
production is an important source of revenues. However, despite the richness of citrus …
production is an important source of revenues. However, despite the richness of citrus …
Synthesis of isatin-tagged thiadiazoles as anti-breast cancer leads: In-vitro and in-silico investigations
J Rasgania, R Gavadia, S Nimesh, L Loveleen… - Journal of Molecular …, 2023 - Elsevier
Despite rapid advances in drug accessibility for diagnosis and treatment, breast cancer
remains a common malignancy among women across the world due to the inadequacy of …
remains a common malignancy among women across the world due to the inadequacy of …
Synthesis, biological evaluation, and molecular modeling studies of new 1, 3, 4‐thiadiazole derivatives as potent antimicrobial agents
In this work, the synthesis, characterization, and biological activities of a new series of 1, 3, 4‐
thiadiazole derivatives were investigated. The structures of final compounds were identified …
thiadiazole derivatives were investigated. The structures of final compounds were identified …
Pyranopyrazoles as efficient antimicrobial agents: green, one pot and multicomponent approach
Innovative therapeutic heterocycles having precisely thiadiazolyl-pyranopyrazole fragments
were prepared by using the ecofriendly synthetic route. Entire compounds formed in …
were prepared by using the ecofriendly synthetic route. Entire compounds formed in …
Antiproliferative-antimicrobial properties and structural analysis of newly synthesized Schiff bases derived from some 1, 3, 4-thiadiazole compounds
Abstract The 1, 3, 4-thiadiazole core has been mainly used as a pharmacological scaffold in
medicinal chemistry. A series of Schiff bases derived from 5-substituted-1, 3, 4-thiadiazole-2 …
medicinal chemistry. A series of Schiff bases derived from 5-substituted-1, 3, 4-thiadiazole-2 …
Quinoxaline-PABA bipartite hybrid derivatization approach: Design and search for antimicrobial agents
In an attempt to find a new class of antimicrobial agents, in the present study we report the
synthesis of bipartite hybrid styryl derivatives of quinoxaline containing para-aminobenzoic …
synthesis of bipartite hybrid styryl derivatives of quinoxaline containing para-aminobenzoic …
Phytochemistry and therapeutic potential of the genus Asphodelus L.: an update
L Nahar, A Al Groshi, L Thangavelu, FMD Ismail… - Phytochemistry …, 2024 - Springer
The genus Asphodelus L.(family: Asphodelaceae) comprises ca. 20 hardy herbaceous,
perennial flowering plant species, and is native to Africa, the Indian subcontinent, the …
perennial flowering plant species, and is native to Africa, the Indian subcontinent, the …
Development of 1, 3, 4-thiadiazole and piperazine fused hybrid quinazoline derivatives as dynamic antimycobacterial agents
Abstract Novel series of 1, 3, 4-thiadiazole and piperazine substituted quinazoline
derivatives have been designed, synthesized, and tested in vitro for antimycobacterial …
derivatives have been designed, synthesized, and tested in vitro for antimycobacterial …
2-(Chloromethyl)-3-phenylquinazolin-4 (3H)-ones as potent anticancer agents; cytotoxicity, molecular docking and in silico studies
In order to show antiproliferation and cancerous cell growth inhibition of quinazoline
derivatives, a series of 2-(chloromethyl)-3-phenylquinazolin-4 (3H)-ones (H 1–H 11) were …
derivatives, a series of 2-(chloromethyl)-3-phenylquinazolin-4 (3H)-ones (H 1–H 11) were …