Dopamine and noradrenaline activate spinal astrocyte endfeet via D1‐like receptors

A Montalant, O Kiehn, JF Perrier - European Journal of …, 2024 - Wiley Online Library
Astrocytes, the most abundant glial cells in the central nervous system, respond to a wide
variety of neurotransmitters binding to metabotropic receptors. Here, we investigated the …

Microglia contact cerebral vasculature through gaps between astrocyte endfeet

GP Morris, CG Foster, BA Sutherland, S Grubb - bioRxiv, 2024 - biorxiv.org
The close spatial relationship between microglia and cerebral blood vessels implicates
microglia in vascular development, homeostasis and disease. In this study we used the …

Ultrastructure of the brain waste-clearance pathway

S Grubb - bioRxiv, 2023 - biorxiv.org
Efficient metabolic waste clearance is essential for optimal brain function. Waste
accumulation can cause inflammation, tissue damage, and potentially lead to dementia and …