Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are clonal
hematopoietic stem cell diseases arising from the bone marrow (BM), and approximately …

Cancer is a leading cause of mortality and morbidity worldwide. Despite major
improvements in current therapeutic methods, ideal therapeutic strategies for improved …

T cell immunoglobulin and mucin domain 3 (TIM-3) expression on malignant cells has been
reported in some leukemias. In myelodysplastic syndrome (MDS), increased TIM-3 …

The tumor microenvironment (TME) influences the occurrence and progression of tumors,
and hypoxia is an important characteristic of the TME. The expression of programmed death …

Escape from immune surveillance is a hallmark of cancer. Immune deregulation caused by
intrinsic and extrinsic cellular factors, such as altered T-cell functions, leads to immune …

Myelodysplastic syndromes (MDS) constitute a very heterogeneous group of diseases with a
high prevalence in elderly patients and a propensity for progression to acute myeloid …

Background Myelodysplastic syndrome (MDS) is a prevalent hematological neoplastic
disorder in clinics and its immunopathogenesis has garnered growing interest. Oral and …

Objective: Osteoarthritis (OA) and Myelodysplastic syndrome (MDS) are diseases caused by
the same immune disorder with unclear etiology and many similarities in clinical …

Myelodysplastic syndromes (MDS) encompass a heterogeneous set of myeloid neoplasms
characterized by ineffective hematopoiesis. Treatment remains challenging, especially for …

Myelodysplastic syndromes (MDS) encompass a heterogeneous set of myeloid neoplasms
characterized by ineffective hema-topoiesis. Treatment remains challenging, especially for …