Primary cilia, antenna-like sensory organelles protruding from the surface of most vertebrate
cell types, are essential for regulating signalling pathways during development and adult …

Ciliogenesis is a complex multistep process used to describe assembly of cilia and flagella.
These organelles play essential roles in motility and signaling on the surface of cells. Cilia …

Primary cilia act as antenna receivers of environmental signals and enable effective
neuronal or glial responses. Disruption of their function is associated with circuit disorders …

Cilia are cellular projections that perform sensory and motile functions in eukaryotic cells. A
defining feature of cilia is that they are evolutionarily ancient, yet not universally conserved …

Oral-facial-digital syndromes (OFDS) are a group of clinically and genetically
heterogeneous disorders characterized by defects in the development of the face and oral …

Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated
by Pericentriolar material 1 (PCM1). To study the requirement for centriolar satellites, we …

Centrosomes are the primary microtubule organizer in eukaryotic cells. In addition to
shaping the intracellular microtubule network and the mitotic spindle, centrosomes are …

Primary cilia play a key role in the ability of cells to respond to extracellular stimuli, such as
signaling molecules and environmental cues. These sensory organelles are crucial to the …

Primary cilia on granule cell neuron progenitors in the developing cerebellum detect sonic
hedgehog to facilitate proliferation. Following differentiation, cerebellar granule cells …

Background: Colorectal cancer (CRC) is the third most common cancer worldwide, in which
aberrant activation of the RAS signaling pathway appears frequently. RAB proteins (RABs) …