Genomic, proteomic, and metabolic comparisons of small animal models of heart failure with preserved ejection fraction: a tale of mice, rats, and cats

AN Smith, R Altara, G Amin, NJ Habeichi… - Journal of the …, 2022 - Am Heart Assoc
Heart failure with preserved ejection fraction (HFpEF) remains a medical anomaly that
baffles researchers and physicians alike. The overall phenotypical changes of diastolic …

Mimicking metabolic disturbance in establishing animal models of heart failure with preserved ejection fraction

H Li, YY Xia, CL Xia, Z Li, Y Shi, XB Li… - Frontiers in …, 2022 - frontiersin.org
Heart failure (HF), the terminal state of different heart diseases, imposed a significant health
care burden worldwide. It is the last battlefield in dealing with cardiovascular diseases. HF …

Emerging therapy for diabetic cardiomyopathy: from molecular mechanism to clinical practice

CF Hsuan, SIF Teng, CN Hsu, D Liao, AJW Chang… - Biomedicines, 2023 - mdpi.com
Diabetic cardiomyopathy is characterized by abnormal myocardial structure or performance
in the absence of coronary artery disease or significant valvular heart disease in patients …

[HTML][HTML] Changes of calcium cycling in HFrEF and HFpEF

J Shou, Y Huo - Mechanobiology in Medicine, 2023 - Elsevier
Dysfunctions of calcium cycling occur in heart failure with reduced and preserved ejection
fraction (HFrEF and HFpEF). HFrEF and HFpEF showed Ca 2+ leakage at diastole. The …

Cardiac diastolic dysfunction by cigarette smoking is associated with mitochondrial integrity in the heart

L Slotabec, H Wang, B Seale, C Wen… - The FASEB …, 2024 - Wiley Online Library
Cigarette smoking behaviors are harmful and cause one out of ten deaths due to
cardiovascular disease. As population sizes grow and number of cigarette smokers …

Proteinopathy: Shared Feature between the Heart and Brain in Alzheimer's Disease

G Amin, GW Booz, FA Zouein - Journal of Cardiovascular …, 2022 - journals.lww.com
Conclusion Although limited, present evidence highlights a systemic feature of AD that
exacerbates the burden on our aging population, namely proteinopathy. There is need for …