Over the past forty years, anthracyclines and ellipticines have attracted attention as
promising cytostatics. In this review, we focus on their mechanisms of cytoxicity, DNA …

Extensive evidence supports involvement of electron transfer (ET), reactive oxygen species
(ROS) and oxidative stress (OS) in the mechanism of many anticancer drugs. The common …

Arsenicosis, due to contaminated drinking water, is a serious health hazard in terms of
morbidity and mortality. Arsenic induced free radicals generated are known to cause cellular …

Arsenic contaminated drinking water has affected more than 200 million people globally.
Chronic arsenicism has also been associated with numerous neurological diseases. One of …

Spiroquinazolinone compounds have been considered as a new series of potent apoptosis-
inducing agents. In this study, anti-proliferative and apoptotic effects of the derivatives from …

Gallium arsenide (GaAs), an intermetallic semiconductor finds widespread applications in
high frequency microwave and millimeter wave, and ultra fast supercomputers. Extensive …

Abstract Background 2, 9-Bis [2-(pyrrolidin-1-yl) ethoxy]-6-{4-[2-(pyrrolidin-1-yl) ethoxy]
phenyl}-11 H-indeno [1, 2-c] quinolin-11-one (BPIQ) is a derivative from 6-arylindeno [1, 2-c] …

Lead, a ubiquitous and potent neurotoxicant causes oxidative stress which leads to
numerous neurobehavioral and physiological alterations. The ability of lead to bind …

Abstract Background 2, 9-Bis [2-(pyrrolidin-1-yl) ethoxy]-6-{4-[2-(pyrrolidin-1-yl) ethoxy]
phenyl}-11 H-indeno [1, 2-c] quinoline-11-one (BPIQ), is a synthetic quinoline analog. A …

Two new derivatives of pyrimido [4′, 5′; 4, 5] thieno (2, 3-b) quinoline (PTQ), 9-hydroxy-4-
(3-diethylaminopropylamino) pyrimido [4′, 5′; 4, 5] thieno (2, 3-b) quinoline (Hydroxy …