Insomnia disorder comprises symptoms during night and day that strongly affect quality of
life and wellbeing. Prolonged sleep latency, difficulties to maintain sleep and early morning …

While insomnia is the second most common mental disorder, progress in our understanding
of underlying neurobiological mechanisms has been limited. The present review addresses …

Cardiovascular diseases (CVDs) are the leading cause of death globally. An effective
strategy to mitigate the burden of CVDs has been to monitor patients' biomedical variables …

Hyperarousal is a key component in all modern etiological models of insomnia disorder.
Overall patterns in the literature suggest that over-active neurobiological and psychological …

Insomnia disorder with objective short sleep duration (less than 6 h of objective sleep or
sleep efficiency less than 85%) has been considered as a biologically severe subtype of …

Abstract Study Objectives Stressful life events contribute to insomnia, psychosocial
functioning, and illness. Though individuals with a history of insomnia may be especially …

Background Generalized anxiety disorder (GAD) and major depressive disorder (MDD)
reliably precede and predict one another. However, there is insufficient data on mediators …

With the rapidly increasing number of patients with chronic disease, numerous recent
studies have put great efforts into achieving long-term health monitoring and patient …

Insomnia disorder is among the most frequent mental disorders, making research on its
aetiology and pathophysiology particularly important. A unifying element of many …

The adaptability of heart to external and internal stimuli is reflected by the heart rate
variability (HRV). Reduced HRV can be a predictor of negative cardiovascular outcomes …