Background Substantial evidence suggests that cognitive deficits might persist after
remission of a major depressive episode. However, results are inconsistent relative to the …

Longitudinal comorbidity of depression and cognitive impairment has been reported by
number of epidemiological studies but the underlying mechanisms explaining the link …

Background Vascular depression is regarded as a subtype of late-life depression
characterized by a distinct clinical presentation and an association with cerebrovascular …

Background We systematically reviewed and meta-analyzed the association of late-life
depression (LLD) with hippocampal volume (HCV) and total brain volume (TBV), and of …

Recent neuroimaging studies have characterized the pathophysiology of late-life depression
(LLD) as a dysfunction of the brain networks involved in the regulation of emotion …

Background Depression's relationship with cerebral abnormalities and cognitive decline is
temporally dynamic. Despite clear clinical utility, understanding depression's effect on …

While mild cognitive impairment (MCI) has been classified into amnestic MCI (aMCI) and
nonamnestic MCI (naMCI), the neuropathological bases of these two subtypes remain …

Brain derived neurotrophic factor (BDNF) is linked to the pathophysiology of depression. We
hypothesized that BDNF is one of the neurobiological pathways related to the augmentation …

An ongoing need exists for innovation in service delivery to ensure that mental health
services deliver high-quality treatment and prevention in the population. This Special Article …

Abstract Background Using the RE-AIM (reach, effectiveness, adoption, implementation,
maintenance) framework, we outline steps taken to implement an evidence-based cognitive …