Mysterious sphingolipids: metabolic interrelationships at the center of pathophysiology
Metabolic pathways are complex and intertwined. Deficiencies in one or more enzymes in a
given pathway are directly linked with genetic diseases, most of them having devastating …
given pathway are directly linked with genetic diseases, most of them having devastating …
Ceramide metabolism enzymes—Therapeutic targets against cancer
A Gomez-Larrauri, U Das Adhikari, M Aramburu-Nuñez… - Medicina, 2021 - mdpi.com
Sphingolipids are both structural molecules that are essential for cell architecture and
second messengers that are involved in numerous cell functions. Ceramide is the central …
second messengers that are involved in numerous cell functions. Ceramide is the central …
Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression
J Lazniewska, KL Li, IRD Johnson, A Sorvina… - Scientific reports, 2023 - nature.com
Prostate cancer (PCa) development and progression relies on the programming of glucose
and lipid metabolism, and this involves alterations in androgen receptor expression and …
and lipid metabolism, and this involves alterations in androgen receptor expression and …
Chaihu-Shugan-San ameliorates tumor growth in prostate cancer promoted by depression via modulating sphingolipid and glycerinphospholipid metabolism
W Li, R Zhou, J Zheng, B Sun, X Jin, M Hong… - Frontiers in …, 2022 - frontiersin.org
Background: Psychologic depression is a pivotal pathological characteristic and has been
shown to promote prostate cancer (PCa) progression. Chaihu-Shugan-San (CSS), a well …
shown to promote prostate cancer (PCa) progression. Chaihu-Shugan-San (CSS), a well …
[HTML][HTML] Nanoliposome C6‐Ceramide in combination with anti‐CTLA4 antibody improves anti‐tumor immunity in hepatocellular cancer
Combination therapy represents an effective therapeutic approach to overcome
hepatocellular cancer (HCC) resistance to immune checkpoint blockade (ICB). Based upon …
hepatocellular cancer (HCC) resistance to immune checkpoint blockade (ICB). Based upon …
Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells
Y Ohya, Y Ogiso, M Matsuda, H Sakae, K Nishida… - Cells, 2024 - mdpi.com
Regulated necrosis, termed necroptosis, represents a potential therapeutic target for
refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic …
refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic …
Solid tumor treatment via augmentation of bioactive C6 ceramide levels with thermally ablative focused ultrasound
Sparse scan partial thermal ablation (TA) with focused ultrasound (FUS) may be deployed to
treat solid tumors and increase delivery of systemically administered therapeutics …
treat solid tumors and increase delivery of systemically administered therapeutics …
[PDF][PDF] Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells. Cells 2024, 13, 405
Y Ohya, Y Ogiso, M Matsuda, H Sakae, K Nishida… - 2024 - researchmap.jp
Regulated necrosis, termed necroptosis, represents a potential therapeutic target for
refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic …
refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic …
[PDF][PDF] Targeted metabolomics revealed a key metabolic reprogramming in cholesterol biosynthesis pathway upon PTEN re-expression in PTEN-null, metastatic and …
TB Güngül - 2022 - repository.bilkent.edu.tr
Taha Buğra Güngül MS in Molecular Biology and Genetics Advisor: Asst. Prof. Onur
Çizmecioğlu June 2022 Prostate cancer is the second most diagnosed type of cancer in …
Çizmecioğlu June 2022 Prostate cancer is the second most diagnosed type of cancer in …