Galectin-3 (Gal-3) is a β-galactoside-binding protein belonging to the lectin family with
pleiotropic regulatory activities and several physiological cellular functions, such as cellular …

Familial hypercholesterolaemia (FH) is under-recognized and under-treated in Europe
leading to significantly higher risk for premature heart disease in those affected. As treatment …

Background and aims Management of familial hypercholesterolaemia (FH) may vary across
different settings due to factors related to population characteristics, practice, resources …

Familial hypercholesterolemia (FH) is a common genetic cause of elevated low-density
lipoprotein cholesterol (LDL-C) due to defective clearance of circulating LDL particles. All FH …

Familial hypercholesterolemia (FH) is the most frequent genetic disease and is
characterized by elevation of LDL-cholesterol that accumulates in tissues leading to …

Genetics of Familial Hypercholesterolemia (FH) is ascribable to pathogenic variants in
genes encoding proteins leading to an impaired LDL uptake by the LDL receptor (LDLR) …

Arterial hypertension is one of the major causes of cardiovascular morbidity and mortality
worldwide. Effective and sustained reduction in blood pressure is essential to reduce …

Hypercholesterolemia represents one key pathophysiological factor predisposing to
increasing risk of developing cardiovascular disease worldwide. Controlling plasma …

Background Familial hypercholesterolemia (FH) may arise from deleterious monogenic
variants in FH‐causing genes as well as from a polygenic cause. We evaluated the …

Background and aims In the association between hypercholesterolemia (HC) and
thrombotic risk platelet hyper-reactivity plays an important role. The inhibition of proprotein …