The challenge of HIV-1 subtype diversity
BS Taylor, ME Sobieszczyk… - … England Journal of …, 2008 - Mass Medical Soc
HIV-1 has evolved multiple mechanisms to elude immune control. The view of virus as
classifiable into distinct subtypes needs to reflect the reality of the constant emergence of …
classifiable into distinct subtypes needs to reflect the reality of the constant emergence of …
HIV drug resistance
F Clavel, AJ Hance - New England Journal of Medicine, 2004 - Mass Medical Soc
Combinations of antiretroviral drugs have proven remarkably effective in controlling the
progression of HIV disease and prolonging survival, but these benefits can be compromised …
progression of HIV disease and prolonging survival, but these benefits can be compromised …
International Con sensus on drug allergy
P Demoly, NF Adkinson, K Brockow, M Castells… - Allergy, 2014 - Wiley Online Library
When drug reactions resembling allergy occur, they are called drug hypersensitivity
reactions (DHR s) before showing the evidence of either drug‐specific antibodies or T cells …
reactions (DHR s) before showing the evidence of either drug‐specific antibodies or T cells …
[图书][B] HIV and the pathogenesis of AIDS.
JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …
has been updated and expanded-now citing more than 2100 references (100 pages of the …
Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications
Human immunodeficiency virus type 1 (HIV-1) is the causative agent of AIDS (10, 38, 105,
114). It is characterized by extensive and dynamic genetic diversity, generating variants …
114). It is characterized by extensive and dynamic genetic diversity, generating variants …
Development of antiretroviral drug resistance
MA Wainberg, GJ Zaharatos… - New England Journal of …, 2011 - Mass Medical Soc
Analysis of HIV drug resistance has identified sites on HIV target genes that convey
resistance to particular classes of agents. These data may be especially important in …
resistance to particular classes of agents. These data may be especially important in …
Unprecedented degree of human immunodeficiency virus type 1 (HIV-1) group M genetic diversity in the Democratic Republic of Congo suggests that the HIV-1 …
N Vidal, M Peeters, C Mulanga-Kabeya… - Journal of …, 2000 - Am Soc Microbiol
The purpose of this study was to document the genetic diversity of human immunodeficiency
virus type 1 (HIV-1) in the Democratic Republic of Congo (DRC; formerly Zaire). A total of …
virus type 1 (HIV-1) in the Democratic Republic of Congo (DRC; formerly Zaire). A total of …
Genotypic testing for human immunodeficiency virus type 1 drug resistance
RW Shafer - Clinical microbiology reviews, 2002 - Am Soc Microbiol
There are 16 approved human immunodeficiency virus type 1 (HIV-1) drugs belonging to
three mechanistic classes: protease inhibitors, nucleoside and nucleotide reverse …
three mechanistic classes: protease inhibitors, nucleoside and nucleotide reverse …
Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance
S Spira, MA Wainberg, H Loemba… - Journal of …, 2003 - academic.oup.com
HIV-1 infection is characterized by genetic diversity wherein distinct viral subtypes (clades A,
B, C, D, E, F, G, K and O) are expanding in different geographical regions. This article deals …
B, C, D, E, F, G, K and O) are expanding in different geographical regions. This article deals …
Travel and the spread of HIV-1 genetic variants
L Perrin, L Kaiser, S Yerly - The Lancet infectious diseases, 2003 - thelancet.com
HIV-1 comprises three groups, the main (M group), O (outlier) and N (non-M, non-O). The M
group, divided into 11 subtypes, is responsible for the global HIV-1 pandemic …
group, divided into 11 subtypes, is responsible for the global HIV-1 pandemic …