Ferroptosis is one of the recently described types of cell death which is dependent on many
factors, including the accumulation of iron and lipid peroxidation. Its induction requires …

Biotherapeutic glycoproteins have revolutionised the field of pharmaceuticals, with new
discoveries and continuous improvements underpinning the rapid growth of this industry. N …

Background Fabry disease (FD) is an X-linked condition caused by variants in the GLA
gene. Since females have two X chromosomes, they were historically thought to be carriers …

Fabry disease is a rare X-linked disease characterized by deficient expression and activity of
alpha-galactosidase A (α-GalA) with consequent lysosomal accumulation of …

Fabry disease (FD) is an X-linked, rare inherited lysosomal storage disease caused by α-
galactosidase A gene variants resulting in deficient or undetectable α-galactosidase A …

The accumulation of globotriaosylceramide (Gb-3) in multiple organs, such as the heart,
kidney, and nervous system, due to mutations in the galactosidase alpha (GLA) gene …

Fabry disease is an X-linked inheritable lysosomal storage disease caused by various
mutations of the galactosidase α gene resulting in α-galactosidase deficiency. Chronic …

Fabry disease (FD), an X-linked disorder resulting from dysfunction of α-galactosidase A,
can result in significant complications. Early intervention yields better outcomes, but …

As the only bionormal nanovesicle, exosomes have high potential as a nanovesicle for
delivering vaccines and therapeutics. We show here that the loading of type-1 membrane …

Abstract α‐Galactosidases are exoglycosidases that are active on galactose‐containing side
chains in oligosaccharides, polysaccharides, glycolipids, and glycoproteins. α …