The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

The association of smoking status with SARS‐CoV‐2 infection, hospitalization and mortality from COVID‐19: a living rapid evidence review with Bayesian meta …

D Simons, L Shahab, J Brown, O Perski - Addiction, 2021 - Wiley Online Library
Aims To estimate the association of smoking status with rates of (i) infection,(ii)
hospitalization,(iii) disease severity and (iv) mortality from SARS‐CoV‐2/COVID‐19 disease …

Effect of convalescent plasma on organ support–free days in critically ill patients with COVID-19: a randomized clinical trial

H Abdelhady, M Abdelrazik, Z Abdi, D Abdo, A Abdulle… - Jama, 2021 - jamanetwork.com
Importance The evidence for benefit of convalescent plasma for critically ill patients with
COVID-19 is inconclusive. Objective To determine whether convalescent plasma would …

COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects

DM Smadja, SJ Mentzer, M Fontenay, MA Laffan… - Angiogenesis, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is presenting as a systemic disease associated with …

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

C Gutmann, K Takov, SA Burnap, B Singh, H Ali… - Nature …, 2021 - nature.com
Prognostic characteristics inform risk stratification in intensive care unit (ICU) patients with
coronavirus disease 2019 (COVID-19). We obtained blood samples (n= 474) from …

Rationale for sequential extracorporeal therapy (SET) in sepsis

C Ronco, L Chawla, F Husain-Syed, JA Kellum - Critical Care, 2023 - Springer
Sepsis and septic shock remain drivers for morbidity and mortality in critical illness. The
clinical picture of patients presenting with these syndromes evolves rapidly and may be …

SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes

Y Li, AM Schneider, A Mehta… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND SARS-CoV-2 plasma viremia has been associated with severe disease and
death in COVID-19 in small-scale cohort studies. The mechanisms behind this association …

COVID-19 and the vasculature: current aspects and long-term consequences

B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …

[HTML][HTML] SARS-CoV-2 placentitis, stillbirth, and maternal COVID-19 vaccination: clinical–pathologic correlations

DA Schwartz, SB Mulkey, DJ Roberts - American journal of obstetrics and …, 2023 - Elsevier
Stillbirth is a recognized complication of COVID-19 in pregnant women that has recently
been demonstrated to be caused by SARS-CoV-2 infection of the placenta. Multiple global …

Asthma in adult patients with COVID-19. Prevalence and risk of severe disease

PD Terry, RE Heidel, R Dhand - American Journal of Respiratory …, 2021 - atsjournals.org
Rationale: Health outcomes of people with coronavirus disease (COVID-19) range from no
symptoms to severe illness and death. Asthma, a common chronic lung disease, has been …