Cell death is a fundamental process in cardiac pathologies. Recent studies have revealed
multiple forms of cell death, and several of them have been demonstrated to underlie …

The ability of isolated brain mitochondria to accumulate, store and release calcium has been
extensively characterized. Extrapolation to the intact neuron led to predictions that the in situ …

Microgravity is associated with immunological dysfunction, though the mechanisms are
poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear …

The human-specific gene ARHGAP11B is preferentially expressed in neural progenitors of
fetal human neocortex and increases abundance and proliferation of basal progenitors …

The G protein–coupled receptor 84 (GPR84), a medium-chain fatty acid receptor, has
garnered attention because of its potential involvement in a range of metabolic conditions …

Respirometry using modified cell culture microplates offers an increase in throughput and a
decrease in biological material required for each assay. Plate based respirometers are …

Functional states of mitochondria are often reflected in characteristic mitochondrial
morphology. One of the most fundamental stress conditions, hypoxia–reoxygenation has …

Key points• Within cells, mitochondria oxidize carbohydrates, and fatty and amino acids to
use the released energy to form ATP, and in the process, they also generate reactive oxygen …

Mitochondrial distribution and motility are recognized as central to many cellular functions,
but their regulation by signaling mechanisms remains to be elucidated. Here, we report that …

Mitochondria are dynamic organelles that undergo frequent remodeling to accommodate
developmental needs. Here, we describe a striking organization of mitochondria into a large …