Introduction Pulmonary vascular dysfunction, pulmonary hypertension (PH), and resulting
right ventricular (RV) failure occur in many critical illnesses and may be associated with a …

Improved outcome of heart failure in response to medical therapy, coupled with a critical
shortage of donor organs, makes it imperative to restrict heart transplantation to patients who …

Background Previous studies have shown that calcium-channel blockers increase morbidity
and mortality in patients with chronic heart failure. We studied the effect of a new calcium …

Avoidance of the clinical syndrome of acute right-sided heart failure after heart
transplantation is, unfortunately, not possible. Clinical experience and the literature certainly …

A. Cyclic nucleotides 112 B. Phosphoinoside hydrolysis ii3 C. Protein kinases 113 D.
Calcium channels 113 E. Potassium channels ii4 VII. Pulmonary vasodilators as therapy 114 …

BACKGROUND: Endothelin receptor antagonism produces favorable short-term
hemodynamic effects in heart failure, but the clinical effects of longer term therapy have not …

Pulmonary hypertension (PH) denotes a poor prognosis in patients with left-sided heart
disease. No study has demonstrated long-term benefit from PH drugs such as prostanoids …

Pulmonary hypertension secondary to degenerative mitral valve disease has been
recognized clinically for many years in veterinary medicine, and clinical diagnosis of this …

The circulation of the lung is unique both in volume and function. For example, it is the only
organ with two circulations: the pulmonary circulation, the main function of which is gas …

Objectives: This study was designed to test the hypothesis of whether amlodipine reduces
the risk for death in patients with heart failure due to a nonischemic cardiomyopathy …