Complex though integrated hormonal and metabolic changes characterize pregnancy. In the
face of progressive decline in insulin action, glucose homeostasis is maintained through a …

Placental growth hormone (PGH) is the product of the GH-V gene, predominantly expressed
in the syncytiotrophoblast layer of the human placenta. PGH differs from pituitary growth …

Human placental growth hormone (PGH), encoded by the growth hormone (GH) variant
gene on chromosome 17, is expressed in the syncytiotrophoblast and extravillous …

Intrauterine tissues (placenta, amnion, chorion, decidua) express hormones and cytokines
that play a decisive role in maternal-fetal physiological interactions. The excessive or …

Diabetes mellitus complicates 1-2% of all pregnancies but is associated with high a
perinatal morbidity and mortality. Gestational diabetes affects up to 4% of pregnancies and …

Context: The human growth hormone/chorionic somatomammotropin (h GH/CSH) locus at
17q22-24, consisting of one pituitary-expressed postnatal (GH1) and four placenta …

Pregnancy and puerperium are periods of intense hormonal changes. Maternal metabolism
adapts to spare the mother from harm on behalf of her developing offspring and major …

As pregnancy progresses the placental syncytiotrophoblast increasingly assumes control of
maternal glucose homeostasis through the release and counter-balancing effects of …

Placental growth hormone (PGH) has been known for 20 years. Nevertheless, its physiology
is far from understood. In this review, basal aspects of PGH physiology are summarised and …

The human GH/CSH cluster consisting of one pituitary-expressed (GH1) and four placenta-
expressed loci has been implicated in maternal metabolic adaptation to pregnancy …