Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

The alarmones guanosine tetraphosphate and guanosine pentaphosphate (collectively
referred to as (p) ppGpp) are involved in regulating growth and several different stress …

Covering: up to early 2011 Streptomycetes and other actinobacteria are renowned as a rich
source of natural products of clinical, agricultural and biotechnological value. They are being …

Streptomycetes are Gram-positive bacteria with a unique capacity for the production of a
multitude of varied and complex secondary metabolites. They also have a complex life cycle …

The control of rRNA synthesis in response to both extra-and intracellular signals has been a
subject of interest to microbial physiologists for nearly four decades, beginning with the …

The genetically well-known strain Streptomyces coelicolor A3 (2) produces the pH indicator
(red/blue) antibiotic actinorhodin, but not all the" blue pigment" produced by this strain is …

Many streptomycetes produce extracellular γ‐butyrolactones. In several cases, these have
been shown to act as signals for the onset of antibiotic production. Synthesis of these …

The N‐terminal region of AfsR, a putative pleiotropic regulatory protein for antibiotic
production in Strepto‐myces coelicolor A3 (2), is homologous to RedD and ActII‐ORF4 …

Deletion of most of the coding region of the ppGpp synthetase gene (relA) of Streptomyces
coelicolor A3 (2) resulted in loss of ppGpp synthesis, both upon entry into stationary phase …

Members of the genus Streptomjces belong to the family Actinomycetales, a division of the
Gram-positive bacteria characterized by a high genomic G+ C content (mean 74 …