Recent advances in NMR-based metabolomics

GA Nagana Gowda, D Raftery - Analytical Chemistry, 2017 - ACS Publications
NMR spectroscopy, one of the two major analytical platforms utilized in the metabolomics
field, has witnessed a large number of advances in fundamental studies, methods …

Cancer metabolomics and the human metabolome database

DS Wishart, R Mandal, A Stanislaus, M Ramirez-Gaona - Metabolites, 2016 - mdpi.com
The application of metabolomics towards cancer research has led to a renewed
appreciation of metabolism in cancer development and progression. It has also led to the …

Integrated metabolomics study of the milk of heat-stressed lactating dairy cows

H Tian, N Zheng, W Wang, J Cheng, S Li, Y Zhang… - Scientific reports, 2016 - nature.com
Heat stress (HS) damages the global dairy industry by reducing milk yields and quality,
harming health, and damaging the reproduction of dairy cows, causing huge economic …

Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients

J Feng, F Zhao, J Sun, B Lin, L Zhao… - … journal of cancer, 2019 - Wiley Online Library
The aim of our study was to investigate the relationship among the gut microbiota
community, metabolite profiles and thyroid carcinoma (TC). First, 30 TC patients and 35 …

Serum metabolomics study of papillary thyroid carcinoma based on HPLC-Q-TOF-MS/MS

Y Du, P Fan, L Zou, Y Jiang, X Gu, J Yu… - Frontiers in cell and …, 2021 - frontiersin.org
This study examined metabolite profile differences between serum samples of thyroid
papillary carcinoma (PTC) patients and healthy controls, aiming to identify candidate …

Metabolomics Analysis in Serum from Patients with Colorectal Polyp and Colorectal Cancer by 1H‐NMR Spectrometry

J Gu, Y Xiao, D Shu, X Liang, X Hu, Y Xie… - Disease …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is one of the leading causes of cancer‐related death worldwide.
Colorectal adenomatous polyps are at high risk for the development of CRC. In this report …

SREBP1 promotes invasive phenotypes by upregulating CYR61/CTGF via the Hippo-YAP pathway

CY Kuo, YC Chang, MN Chien… - Endocrine-Related …, 2022 - erc.bioscientifica.com
Aberrant lipid metabolism provides bioenergetic, biosynthetic, and redox supplies to cancer
cells. Previous studies have reported differential lipid profiling in thyroid malignancies. Sterol …

Metabolomic profiling of CSF in multiple sclerosis and neuromyelitis optica spectrum disorder by nuclear magnetic resonance

HH Kim, IH Jeong, JS Hyun, BS Kong, HJ Kim, SJ Park - PloS one, 2017 - journals.plos.org
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are
inflammatory diseases of the central nervous system. Although several studies have …

Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice

Y Tian, B Rimal, JE Bisanz, W Gui… - Environmental …, 2024 - ehp.niehs.nih.gov
Background: Exposure to persistent organic pollutants (POPs) and disruptions in the
gastrointestinal microbiota have been positively correlated with a predisposition to factors …

ACLY inhibitors induce apoptosis and potentiate cytotoxic effects of sorafenib in thyroid cancer cells

SS Huang, CH Tsai, CY Kuo, YS Li, SP Cheng - Endocrine, 2022 - Springer
Purpose ATP-citrate lyase (ACLY) is a critical enzyme at the intersection of glucose and lipid
metabolism. ACLY is often upregulated or activated in cancer cells to accelerate lipid …