Crystal engineering of pharmaceutical cocrystals in the discovery and development of improved drugs

G Bolla, B Sarma, AK Nangia - Chemical reviews, 2022 - ACS Publications
The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

Sustainability assessment of mechanochemistry by using the twelve principles of green chemistry

KJ Ardila‐Fierro, JG Hernández - ChemSusChem, 2021 - Wiley Online Library
In recent years, mechanochemistry has been growing into a widely accepted alternative for
chemical synthesis. In addition to their efficiency and practicality, mechanochemical …

The mechanochemical synthesis of polymers

A Krusenbaum, S Grätz, GT Tigineh… - Chemical Society …, 2022 - pubs.rsc.org
Mechanochemistry–the utilization of mechanical forces to induce chemical reactions–is a
rarely considered tool for polymer synthesis. It offers numerous advantages such as reduced …

Advancing mechanochemical synthesis by combining milling with different energy sources

V Martinez, T Stolar, B Karadeniz, I Brekalo… - Nature Reviews …, 2023 - nature.com
Owing to its efficiency and unique reactivity, mechanochemical processing of bulk solids has
developed into a powerful tool for the synthesis and transformation of various classes of …

Mechanochemistry: new tools to navigate the uncharted territory of “impossible” reactions

F Cuccu, L De Luca, F Delogu, E Colacino… - …, 2022 - Wiley Online Library
Mechanochemical transformations have made chemists enter unknown territories, forcing a
different chemistry perspective. While questioning or revisiting familiar concepts belonging …

Mechanochemistry for synthesis

T Friščić, C Mottillo, HM Titi - Angewandte Chemie, 2020 - Wiley Online Library
Mechanochemical solvent‐free reactions by milling, grinding or other types of mechanical
action have emerged as a viable alternative to solution chemistry. Mechanochemistry offers …

Liquid‐assisted grinding mechanochemistry in the synthesis of pharmaceuticals

P Ying, J Yu, W Su - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
Mechanochemical reactions by milling, grinding or other types of mechanical action have
emerged as a salient green approach because of its wide applications towards academic …

Redox reactions of small organic molecules using ball milling and piezoelectric materials

K Kubota, Y Pang, A Miura, H Ito - Science, 2019 - science.org
Over the past decade, photoredox catalysis has harnessed light energy to accelerate bond-
forming reactions. We postulated that a complementary method for the redox-activation of …

Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

JL Howard, Q Cao, DL Browne - Chemical science, 2018 - pubs.rsc.org
Mechanochemistry is becoming more widespread as a technique for molecular synthesis
with new mechanochemical reactions being discovered at increasing frequency. Whilst …

Mechanochemistry: a force of synthesis

JL Do, T Friščić - ACS central science, 2017 - ACS Publications
The past decade has seen a reawakening of solid-state approaches to chemical synthesis,
driven by the search for new, cleaner synthetic methodologies. Mechanochemistry, ie …