The year 2009 marked the fiftieth anniversary of the first successful allogeneic
haematopoietic stem cell transplant (HSCT). The field of HSCT has pioneered some of the …

BACKGROUND Fertility in adult life may be severely impaired by gonadotoxic therapies. For
young boys who do not yet produce spermatozoa, cryopreservation of immature testicular …

In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune
diseases (ADs) were published, while an international coordinated clinical programme was …

Although modern clinical management strategies have improved the outcome of paediatric
patients with severe autoimmune and inflammatory diseases over recent decades, a …

Autologous and allogeneic hematopoietic stem cell transplantation (HSCT) can be used in
the management of patients with autoimmune disorders. Because the experience with …

OBJECTIVES: To provide an overview of the indications for hematopoietic stem cell
transplantation (HSCT), including standard-of-care and experimental diseases. DATA …

Stem cell transplant (SCT) has long been the standard of care for several hematologic,
immunodeficient, and oncologic disorders. Recently, SCT has become an increasingly …

Theoretical and practical basis for early aggressive therapy... : Current Opinion in Rheumatology
Theoretical and practical basis for early aggressive therapy in paediatric autoimmune disorders …

Many new therapies are emerging that use hematopoietic stem and progenitor cells. In this
review, we focus on five promising emerging trends that are altering stem cell usage in …

In children, autoimmune diseases and their therapies cause significant morbidity, especially
in those with severe or refractory disease. The constant development of new …