Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
Strategies to improve the EPR effect: A mechanistic perspective and clinical translation
Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …
their efficacy and to reduce their adverse effects. These efforts include the development of …
Three-dimensional spheroids as in vitro preclinical models for cancer research
Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture
techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority …
techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority …
Current trends and challenges in cancer management and therapy using designer nanomaterials
Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …
therapeutic formulations. In fact, significant strides have been made towards the application …
Antibiotic resistance in aquaculture and aquatic organisms: a review of current nanotechnology applications for sustainable management
Aquaculture has emerged as one of the world's fastest-growing food industries in recent
years, helping food security and boosting global economic status. The indiscriminate …
years, helping food security and boosting global economic status. The indiscriminate …
Gold nanoparticles as radiosensitizers in cancer radiotherapy
Y Chen, J Yang, S Fu, J Wu - International Journal of …, 2020 - Taylor & Francis
The rapid development of nanotechnology offers a variety of potential therapeutic strategies
for cancer treatment. High atomic element nanomaterials are often utilized as …
for cancer treatment. High atomic element nanomaterials are often utilized as …
Emerging ultrasmall luminescent nanoprobes for in vivo bioimaging
Photoluminescence (PL) imaging has become a fundamental tool in disease diagnosis,
therapeutic evaluation, and surgical navigation applications. However, it remains a big …
therapeutic evaluation, and surgical navigation applications. However, it remains a big …
Engineered nanomedicines with enhanced tumor penetration
Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …
Smart transformable nanoparticles for enhanced tumor theranostics
The physical morphologies of nanoparticles, especially size and shape, always significantly
influence their biological behaviors. In the past, nanoparticles with constant physical …
influence their biological behaviors. In the past, nanoparticles with constant physical …
Size-tunable strategies for a tumor targeted drug delivery system
W Yu, R Liu, Y Zhou, H Gao - ACS central science, 2020 - ACS Publications
Nanoparticles have been widely used in tumor targeted drug delivery, while the antitumor
effects are not always satisfactory due to the limited penetration and retention. As we all …
effects are not always satisfactory due to the limited penetration and retention. As we all …