Discovered more than 30 years ago, the angiotensin AT 2 receptor (AT 2 R) has evolved
from a binding site with unknown function to a firmly established major effector within the …

Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …

Statins are a class of widely prescribed drugs used to reduce low-density lipoprotein
cholesterol (LDL-C) and important to prevent cardiovascular diseases (CVD). Most statin …

The renin–angiotensin system (RAS) is one of the most complex hormonal regulatory
systems, involving several organs that interact to regulate multiple body functions. The study …

A bidirectional relationship exists between hypertension and psychiatric disorders, including
unipolar and bipolar depression, anxiety, post-traumatic stress disorder (PTSD), psychosis …

Lumbar intervertebral disc degeneration (IDD) has been the major contributor to low back
pain (LBP). IDD is an chronic inflammation process, with the activation of plentiful …

The Renin–Angiotensin System (RAS) has attracted considerable interest beyond its
traditional cardiovascular role due to emerging data indicating its potential involvement in …

Brain neurodegenerative diseases (BND) are debilitating conditions that are especially
characteristic of a certain period of life and considered major threats to human health …

Traumatic brain injury (TBI) alters brain function and is a crucial public health concern
worldwide. TBI triggers the release of inflammatory mediators (cytokines) that aggravate …

A growing body of evidence suggests that patients who experience traumatic brain injuries
(TBIs) exhibit significantly shorter healing periods compared to those with isolated fractures …