BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …

Introduction This study aimed to investigate if maternal pregnancy exposure to metformin is
associated with increased risk of long-term and short-term adverse outcomes in the child …

Objective To investigate whether exposure to metformin during the first trimester of
pregnancy, for diabetes or other indications, increases the risk of all or specific congenital …

OBJECTIVE To assess the risk of major congenital malformations with metformin versus
insulin in pregnancies with type 2 diabetes. RESEARCH DESIGN AND METHODS This …

Metformin is considered as first-line treatment for type 2 diabetes and an effective treatment
for polycystic ovary syndrome (PCOS). However, evidence regarding its safety in pregnancy …

Once a woman is diagnosed with gestational diabetes mellitus (GDM), two strategies are
considered for management; life-style modifications and pharmacological therapy. The …

Objective Diabetes in pregnancy and consequently the need for treatment with antidiabetic
medication (ADM) has become increasingly prevalent. The prevalence and patterns of use …

Abstract Context and Aim Metformin has been used in pregnancy since the 1970s. It is
cheap, widely available and is acceptable to women. Despite its increasing use, controversy …

Aims To examine risk of adverse pregnancy outcomes, mothers' characteristics and
incidence rate over time of pregestational type 1 (T1D), type 2 (T2D) or gestational diabetes …